섬유성 이형성증 (Fibrous Dysplasia)의 특징적인 영상 소견은?

심화 해설

임상 시나리오

핵심 개념

• Fibrous Dysplasia — A benign bone disorder where normal bone is replaced with fibrous tissue and immature woven bone, leading to structural weakness and potential deformities.
• Ground Glass Opacity — A radiographic appearance on X-ray characterized by a hazy, homogeneous increase in density that resembles ground glass, often seen in fibrous dysplasia due to the mixture of fibrous and bony elements.
• Lytic Lesion — An area of bone destruction or resorption that appears as a dark or lucent area on imaging, indicative of conditions like fibrous dysplasia where bone is replaced by abnormal tissue.
• McCune-Albright Syndrome — A rare genetic disorder characterized by polyostotic fibrous dysplasia, cafe-au-lait skin spots, and endocrine abnormalities such as precocious puberty, resulting from postzygotic mutations in the GNAS gene.
• Cortical Thinning — A reduction in the thickness of the cortical bone, often observed in fibrous dysplasia as the lesion expands and erodes the inner cortex, increasing the risk of fractures.