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Which feature of a pigmented skin lesion MOST warrants referral for evaluation?

• 1 A lesion that is identical in appearance to several others nearby
• 2 Asymmetry with irregular borders, color variation, and recent change in size ✓ 정답
• 3 A uniformly brown round lesion that has been unchanged for many years
• 4 A small symmetric lesion with sharply defined regular borders present

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