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학습 자료 둘러보기 →In a transplant recipient on immunosuppressive therapy, any new symptom like fatigue, persistent cough, or oral white patches is a sentinel finding for an opportunistic infection. The priority is to obtain specimens for culture and notify the provider immediately.
The oral lesions are consistent with oropharyngeal candidiasis, but the cough raises concern for invasive candidiasis or another systemic infection. In immunocompromised hosts, localized fungal infections can rapidly progress to candidemia, which has a mortality rate exceeding 40%.
Never attribute these symptoms to minor causes or delay intervention. Do not increase immunosuppression, as this will exacerbate the infection. Early antifungal therapy is critical for graft and patient survival.
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