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학습 자료 둘러보기 →In a client with cirrhosis presenting with lethargy, disorientation, and asterixis, the priority is to administer lactulose. This directly targets the underlying hyperammonemia by acidifying the colon to trap ammonia and exerting a cathartic effect to expel it.
Lactulose is titrated to achieve 2 to 3 soft bowel movements per day. Improvement in mental status confirms the diagnosis and treatment efficacy. Supportive measures like safety precautions are secondary to this specific pharmacological intervention.
Do not delay lactulose administration for neuro checks or protein restriction. Routine dietary protein restriction is no longer recommended as it worsens malnutrition without clear benefit in acute HE. Monitor for over-diarrhea which can cause dehydration and electrolyte imbalance.
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