A jaundiced patient has an increased total bilirubin that is predominantly unconjugated, with a normal alkaline phosphatase and an increased reticulocyte count. Which cause is most likely?
1Biliary obstruction
2Drug-induced cholestasis
3Acute hepatitis
4Hemolysis✓ 정답
해설
When many red cells are destroyed, the load of bilirubin to be conjugated exceeds capacity and unconjugated bilirubin accumulates. The marrow compensates, so the reticulocyte count rises. Biliary obstruction would instead raise conjugated bilirubin along with alkaline phosphatase.