A patient with ongoing hemolysis has frequent high glucose m… | 마이메르시 MyMerci
Chemistry · 임상화학
문제
A patient with ongoing hemolysis has frequent high glucose measurements but an unexpectedly low HbA1c. What is the best explanation?
1Hemolysis prolongs red cell survival and increases glycation
2Shortened red cell survival reduces the time available for hemoglobin glycation✓ 정답
3Glucose meters measure only glycated hemoglobin
4Unconjugated bilirubin is converted directly into HbA1c
해설
HbA1c depends on glucose exposure over the red cell lifespan. Increased turnover and shortened survival can produce a falsely low result relative to the patient's true glycemia.
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