A patient with ongoing hemolysis has frequent high glucose m… | 마이메르시 MyMerci
이 문제가 수록된 문제집미국 임상병리사 MLS(ASCP/ASCPi) 문제은행·CAT문제집 보기
Chemistry · 임상화학
문제
A patient with ongoing hemolysis has frequent high glucose measurements but an unexpectedly low HbA1c. What is the best explanation?
1Hemolysis prolongs red cell survival, allowing more time for hemoglobin glycation and raising HbA1c
2Shortened red cell survival reduces the time available for hemoglobin glycation, lowering HbA1c✓ 정답
3Glucose meters measure only glycated hemoglobin, so they overestimate plasma glucose in hemolysis
4Unconjugated bilirubin is converted directly into HbA1c, falsely lowering the measured percentage
해설
HbA1c depends on glucose exposure over the red cell lifespan. Increased turnover and shortened survival can produce a falsely low result relative to the patient's true glycemia.