A patient has total calcium 7.6 mg/dL, albumin 2.0 g/dL, and ionized calcium within the reference interval. Wh…

Question

A patient has total calcium 7.6 mg/dL, albumin 2.0 g/dL, and ionized calcium within the reference interval. Which explanation best accounts for the results?

Accepted Answer

보기 2: Low albumin decreased the protein-bound fraction and produced a low total calcium result

A substantial portion of total calcium is albumin-bound. Hypoalbuminemia can lower total calcium while biologically active ionized calcium remains normal; ionized measurement or an appropriate correction is used to confirm true hypocalcemia.

Answer

보기 1: The patient has severe ionized hypocalcemia due to parathyroid hormone deficiency

Answer

보기 3: EDTA contamination in the sample tube selectively increased ionized calcium measurement

Answer

보기 4: Hyperalbuminemia caused calcium to shift into cells, lowering total serum calcium levels

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A patient has total calcium 7.6 mg/dL, albumin 2.0 g/dL, and ionized calcium within the reference interval. Which explanation best accounts for the results?

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