A patient has a markedly increased alkaline phosphatase and gamma-glutamyl transferase with only mildly increased aminotransferases. Which pattern does this suggest?
1Cholestatic or obstructive liver disease✓ 정답
2Hepatocellular injury
3Bone disease without liver involvement
4Acute viral hepatitis
해설
Liver enzyme elevations fall into two patterns. A predominant rise in aminotransferases indicates hepatocellular injury, whereas a predominant rise in alkaline phosphatase indicates cholestasis. A concurrent rise in gamma-glutamyl transferase confirms that the alkaline phosphatase originates from the liver rather than from bone.