A patient has a markedly increased alkaline phosphatase and gamma-glutamyl transferase with only mildly increa…

Question

A patient has a markedly increased alkaline phosphatase and gamma-glutamyl transferase with only mildly increased aminotransferases. Which pattern does this suggest?

Accepted Answer

보기 1: Cholestatic or obstructive liver disease

Liver enzyme elevations fall into two patterns. A predominant rise in aminotransferases indicates hepatocellular injury, whereas a predominant rise in alkaline phosphatase indicates cholestasis. A concurrent rise in gamma-glutamyl transferase confirms that the alkaline phosphatase originates from the liver rather than from bone.

Answer

보기 2: Hepatocellular injury

Answer

보기 3: Bone disease without liver involvement

Answer

보기 4: Acute viral hepatitis

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A patient has a markedly increased alkaline phosphatase and gamma-glutamyl transferase with only mildly increased aminotransferases. Which pattern does this suggest?

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