A 70-year-old patient has a white cell count of 80,000 per microliter composed mainly of small mature lymphocytes, with numerous smudge cells on the smear. Which condition is most likely?
1Acute lymphoblastic leukemia
2Chronic lymphocytic leukemia✓ 정답
3Infectious mononucleosis
4Hairy cell leukemia
해설
Advanced age, an absolute increase in mature lymphocytes, and smudge cells together indicate chronic lymphocytic leukemia. Smudge cells arise because the fragile cells rupture during smear preparation. Acute lymphoblastic leukemia is dominated by immature blasts.