A sickle solubility screen is positive. Which next test best… | 마이메르시 MyMerci
Hematology · 혈액학·지혈
문제
A sickle solubility screen is positive. Which next test best distinguishes sickle trait from sickle cell disease and identifies the hemoglobin fractions?
1Erythrocyte sedimentation rate
2Osmotic fragility alone
3Hemoglobin analysis such as HPLC or electrophoresis✓ 정답
4Bleeding time
해설
A solubility screen detects the presence of HbS but does not define the hemoglobin pattern. Hemoglobin separation or analysis quantifies HbS, HbA, HbF, and other fractions needed for classification.
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