Several days after starting an oxidant drug, a patient develops anemia. The smear shows bite cells, and a supr…

Question

Several days after starting an oxidant drug, a patient develops anemia. The smear shows bite cells, and a supravital stain reveals Heinz bodies. Which deficiency is most likely?

Accepted Answer

보기 1: Glucose-6-phosphate dehydrogenase deficiency

Oxidative damage denatures hemoglobin into Heinz bodies, and the spleen removes those inclusions, producing bite cells. The characteristic features are an oxidative trigger such as a drug or infection and an episodic presentation.

Answer

보기 2: Pyruvate kinase deficiency of the glycolytic pathway

Answer

보기 3: Hereditary elliptocytosis of the red cell membrane

Answer

보기 4: Paroxysmal nocturnal hemoglobinuria with hemolysis

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Several days after starting an oxidant drug, a patient develops anemia. The smear shows bite cells, and a supravital stain reveals Heinz bodies. Which deficiency is most likely?

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