A patient has an MCV of 115 fL, hypersegmented neutrophils on the smear, and a mild pancytopenia. Which deficiency is most likely?
1Iron
2Vitamin K
3Pyridoxine
4Vitamin B12 or folate✓ 정답
해설
Macrocytosis together with hypersegmented neutrophils indicates megaloblastic anemia caused by vitamin B12 or folate deficiency. Delayed DNA synthesis makes the cells large while nuclear maturation lags behind. Iron deficiency is microcytic and vitamin K deficiency affects coagulation.