An isolated prolonged aPTT corrects into the reference inter… | 마이메르시 MyMerci
이 문제가 수록된 문제집미국 임상병리사 MLS(ASCP/ASCPi) 문제은행·CAT문제집 보기
Hematology · 혈액학·지혈
문제
An isolated prolonged aPTT corrects into the reference interval immediately after a 1:1 mix with normal plasma. What does this pattern most strongly suggest?
1A strong immediately acting inhibitor that neutralizes coagulation factors and disrupts the assay
2Excess platelets that release platelet factor 4 and interfere with heparin activity in the test
3Specimen lipemia only that optically obscures the clot detection endpoint and prolongs clotting
4A deficiency of one or more factors supplied by normal plasma✓ 정답
해설
Correction after mixing indicates that normal plasma supplied a missing coagulation factor. Failure to correct suggests an inhibitor, although time-dependent inhibitors require incubated interpretation.