Abnormal promyelocytes with heavy granulation and bundles of… | 마이메르시 MyMerci
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Hematology · 혈액학·지혈
문제
Abnormal promyelocytes with heavy granulation and bundles of Auer rods are seen in a patient with disseminated intravascular coagulation. Which molecular finding is most characteristic?
1BCR::ABL1
2JAK2 V617F
3PML::RARA✓ 정답
4MYD88 L265P
해설
Acute promyelocytic leukemia is characteristically associated with PML::RARA, usually from t(15;17), and has a strong association with coagulopathy and DIC.