Which measure is most effective in preventing recurrent febrile nonhemolytic transfusion reactions?
1Washing red cells before transfusion
2Irradiating the components
3Premedicating with antihistamines
4Using leukocyte-reduced components✓ 정답
해설
Febrile nonhemolytic reactions are caused by leukocytes and leukocyte-derived cytokines, so leukocyte-reduced components are the definitive preventive measure. Washing addresses allergic reactions, irradiation prevents graft-versus-host disease, and antihistamines do not prevent fever.