A newborn requires an exchange transfusion for hemolytic disease caused by maternal anti-D. Which red cell uni…

Question

A newborn requires an exchange transfusion for hemolytic disease caused by maternal anti-D. Which red cell unit is most appropriate?

Accepted Answer

보기 1: Group O, D negative, compatible with the maternal serum

The maternal anti-D is what destroys the red cells of the infant, so the unit must be D negative and compatible with the maternal serum. In neonatal testing the serum of the mother is the source of antibody, so compatibility is assessed against the maternal sample.

Answer

보기 2: Group O, D positive, crossmatch compatible with the infant

Answer

보기 3: Group specific to the infant, D positive

Answer

보기 4: Group AB, D negative

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A newborn requires an exchange transfusion for hemolytic disease caused by maternal anti-D. Which red cell unit is most appropriate?

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