An antibody identification panel shows reactivity only with cells positive for the K antigen. How many antigen-positive and antigen-negative cells are generally required to confirm the identification with statistical confidence?
1Two positive and two negative
2Five positive and one negative
3One positive and five negative
4Three positive and three negative✓ 정답
해설
Statistical confidence requires reactivity with three antigen-positive cells and no reactivity with three antigen-negative cells. This is the 3-and-3 rule, which lowers the probability of a chance match to an acceptable level. If the rule is not satisfied, additional selected cells must be tested.