An antibody identification panel shows reactivity only with cells positive for the K antigen. How many antigen…

Question

An antibody identification panel shows reactivity only with cells positive for the K antigen. How many antigen-positive and antigen-negative cells are generally required to confirm the identification with statistical confidence?

Accepted Answer

보기 4: Three positive and three negative

Statistical confidence requires reactivity with three antigen-positive cells and no reactivity with three antigen-negative cells. This is the 3-and-3 rule, which lowers the probability of a chance match to an acceptable level. If the rule is not satisfied, additional selected cells must be tested.

Answer

보기 1: Two positive and two negative

Answer

보기 2: Five positive and one negative

Answer

보기 3: One positive and five negative

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An antibody identification panel shows reactivity only with cells positive for the K antigen. How many antigen-positive and antigen-negative cells are generally required to confirm the identification with statistical confidence?

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