Why is routine reverse ABO grouping generally not interprete… | 마이메르시 MyMerci
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Blood Banking · 수혈의학
문제
Why is routine reverse ABO grouping generally not interpreted in a newborn in the same way as in an adult?
1Newborn red cells have no ABO antigens, so reverse grouping would show no agglutination
2Expected anti-A and anti-B are not reliably developed in early infancy, leading to false negatives✓ 정답
3Cord plasma always contains maternal anti-D, which can interfere with reverse ABO grouping reactions
4Forward grouping cannot be performed on newborn red cells due to weak antigen expression
해설
Naturally occurring ABO antibodies are not reliably present in early infancy. Newborn ABO determination therefore relies principally on forward grouping with appropriate specimen precautions.