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학습 자료 둘러보기 →For a patient on lorazepam 2 mg twice daily for 6 months, the priority is a provider-directed gradual taper. Abrupt or rapid self-discontinuation risks a severe withdrawal syndrome including seizures and psychosis.
The most current evidence supports hyperbolic tapering, where doses are reduced by progressively smaller amounts proportional to the current dose. This accounts for the drug's receptor occupancy curve, minimizing neuroexcitation and withdrawal symptoms compared to linear reductions.
Never advise a patient to abruptly stop or independently halve their benzodiazepine dose. These actions can precipitate life-threatening autonomic instability. Always collaborate with the prescriber to establish a safe, individualized tapering plan.
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