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학습 자료 둘러보기 →A serum albumin level below 3.5 g/dL is a critical marker. A level of 2.8 g/dL indicates severe protein depletion, directly impairing collagen synthesis and fibroblast function needed for skin repair.
Low albumin reduces oncotic pressure, leading to edema. This edema increases the diffusion distance for oxygen and nutrients, making the dermis and epidermis hypoxic and highly susceptible to breakdown from pressure, friction, and shear.
In older adults, hypoalbuminemia synergizes with inflammaging, a chronic low-grade inflammation, exponentially increasing the risk of skin breakdown and delayed wound healing. Always assess prealbumin for a more current nutritional picture.
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