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Pharmacology
문제

A nurse is caring for a patient receiving morphine sulfate via patient-controlled analgesia (PCA) pump for postoperative pain management. Which assessment finding would require the nurse to take immediate action?

해설
Respiratory rate of 8 breaths/min with shallow breathing indicates severe opioid-induced respiratory depression, requiring immediate intervention like stopping PCA and notifying the provider. Other findings (pain 6/10, drowsiness arousable to stimuli, slight BP drop) are expected or less critical.
같은 주제 다음 문제A nurse is assessing a patient who has been receiving morphine sulfate 10 mg IV every 4 ho…

심화 해설

Understanding the Priority: Airway, Breathing, Circulation
The NCLEX-RN frequently tests your ability to prioritize care using the ABC (Airway, Breathing, Circulation) framework. In a patient receiving opioid analgesics like morphine, the most life-threatening risk is opioid-induced respiratory depression (OIRD). This condition is insidious and can progress from subtle sedation to respiratory arrest and cardiorespiratory collapse within minutes, even in patients considered low-risk [1]. Your immediate action must target the finding that signals a critical compromise in breathing.

Analysis of Assessment Findings

Option 1: Patient reports pain level of 6/10 on numeric rating scale
A pain score of 6/10 indicates moderate pain that requires intervention, such as evaluating the PCA pump settings, checking for occlusions in the IV line, or considering adjunctive non-opioid analgesics. While unrelieved pain is a serious concern that can impede recovery, it does not represent an immediate threat to the patient’s life. Addressing this is important but is a lower priority than a breathing emergency.

Option 2: Patient appears drowsy but arouses easily to verbal stimuli
A patient who is drowsy but easily arousable is exhibiting an expected level of sedation from opioid therapy. This finding indicates the patient is on the continuum of sedation but is currently protecting their own airway and maintaining adequate ventilation. The appropriate nursing action is to continue frequent monitoring using a validated sedation scale, but this does not require an emergent intervention. The critical threshold is when sedation progresses to the point where the patient is difficult to arouse or cannot protect their airway.

Option 3: Patient's blood pressure is 110/70 mmHg (baseline 120/80 mmHg)
This blood pressure reading represents a mild decrease from baseline. Morphine can cause vasodilation and a slight drop in blood pressure. A reading of 110/70 mmHg is within a normotensive range and is not a sign of hemodynamic instability. While you would continue to monitor this trend, it is not the finding that requires the most immediate action.

Option 4: Patient's respiratory rate is 8 breaths per minute with shallow breathing
This is the priority finding. A respiratory rate of 8 breaths per minute with shallow depth is the clinical hallmark of opioid-induced respiratory depression (OIRD). The pathophysiology involves morphine binding to mu-opioid receptors in the brainstem’s respiratory centers, blunting its sensitivity to rising carbon dioxide (CO2) levels. This leads to a progressive decrease in both respiratory rate and tidal volume. As documented in the literature, OIRD can have a subtle onset, and a critically low respiratory rate signifies that the patient is already in a state of hypoventilation and is at high risk for hypercapnia, hypoxemia, and complete respiratory arrest [1]. The nurse’s immediate action is to stimulate the patient, administer supplemental oxygen, prepare to administer an opioid antagonist like naloxone per protocol, and stay with the patient while calling for the rapid response team.
References (research sources)
  • [1]
    Insidious opioid-induced respiratory depression following abdominal steel pipe perforation injury: A case report.Case reportZhang X, Qiao S, Pan H. (2025) · DOI: 10.1097/md.0000000000045435

임상 시나리오

Opioid PCA Safety MonitoringPrioritizing Respiratory Depression over Sedation

The most critical adverse effect of opioid therapy is opioid-induced respiratory depression (OIRD). A respiratory rate of 8 breaths/min with shallow breathing signifies a compromised airway and requires immediate intervention per the ABC framework.

Sedation is a precursor to OIRD. Use a validated sedation scale (e.g., Pasero Opioid-Induced Sedation Scale) with every assessment. A patient who is drowsy but easily arousable is at an acceptable level of sedation, whereas a patient who is somnolent or difficult to arouse is at high risk.

Caution

Do not rely on pulse oximetry alone. Capnography provides the earliest detection of hypoventilation. If respiratory depression occurs, the first action is to stimulate the patient and call for help, followed by administering naloxone as prescribed.

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