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Pharmacology
문제

A nurse is caring for a patient receiving morphine sulfate via patient-controlled analgesia (PCA) pump. Which assessment finding requires the nurse's immediate intervention?

해설
Respiratory rate of 8 breaths/min with shallow breathing indicates severe opioid-induced respiratory depression requiring immediate intervention. Other findings (pain, mild hypotension, drowsiness) are expected or less urgent.
같은 주제 다음 문제A nurse is assessing a patient who has been receiving morphine sulfate 10 mg IV every 4 ho…

심화 해설

Understanding the Priority: Airway and Breathing
When using a PCA pump, the most critical adverse effect to monitor for is opioid-induced respiratory depression (OIRD). The provided case report highlights that OIRD can have an insidious onset and progress rapidly to cardiorespiratory collapse, even in patients without traditional risk factors [1]. In the NCLEX-RN prioritization framework, an assessment finding indicating a compromised airway or breathing pattern always takes precedence over pain or mild changes in consciousness.

Analysis of Assessment Findings
The nurse must differentiate between expected therapeutic effects, manageable side effects, and life-threatening complications of morphine sulfate.

- Option 1: A pain level of 6/10 indicates inadequate analgesia. While this requires intervention, such as evaluating the PCA settings or considering adjuvant therapy, unrelieved pain is not immediately life-threatening. The patient’s airway and breathing are currently stable.
- Option 2: A blood pressure of 110/70 mmHg from a baseline of 120/80 mmHg represents a mild decrease. Morphine causes vasodilation and can lower blood pressure, but this reading remains within a normotensive range and does not signal hemodynamic instability.
- Option 3: Drowsiness where the patient arouses easily to verbal stimuli is a common and expected effect of opioid therapy, reflecting sedation without a compromised airway. The key safety distinction here is that the patient is easily arousable, meaning protective airway reflexes are likely intact.
- Option 4: A respiratory rate of 8 breaths per minute with shallow breathing is the classic clinical presentation of OIRD. Opioids bind to mu-receptors in the brainstem’s respiratory centers, blunting the responsiveness to rising carbon dioxide levels. This finding indicates that the patient’s ventilation is critically compromised, which can lead to hypercapnia, hypoxemia, and eventual respiratory arrest [1].

Clinical Reasoning and Immediate Action
The nurse must recognize that a respiratory rate below 10 breaths per minute in an adult receiving opioids signifies severe respiratory depression. The shallow depth further reduces alveolar ventilation. This scenario directly aligns with the pathophysiology described in the case report, where the subtle progression of OIRD can quickly become fatal if not promptly identified and reversed [1]. The immediate nursing intervention is to stop the PCA pump, administer supplemental oxygen, vigorously stimulate the patient to breathe, and prepare to administer an opioid antagonist like naloxone as prescribed.
References (research sources)
  • [1]
    Insidious opioid-induced respiratory depression following abdominal steel pipe perforation injury: A case report.Case reportZhang X, Qiao S, Pan H. (2025) · DOI: 10.1097/md.0000000000045435

임상 시나리오

Responding to PCA-Related Respiratory DepressionImmediate nursing actions for a patient with a respiratory rate of 8/min

The priority is to immediately stop the opioid infusion via the PCA pump. A respiratory rate below 10 breaths per minute with shallow breathing is a critical sign of opioid-induced respiratory depression (OIRD).

Stimulate the patient and administer naloxone as prescribed. Naloxone is an opioid antagonist that reverses respiratory depression. The typical initial dose is 0.4 mg to 2 mg IV, repeated every 2 to 3 minutes as needed, with a lower dose for postoperative patients to avoid a sudden return of severe pain.

Maintain a patent airway and provide ventilatory support with a bag-valve-mask delivering 100% oxygen if the patient is not breathing adequately. Continuous monitoring of oxygen saturation and end-tidal CO2 (capnography) is essential, as capnography provides the earliest indication of respiratory depression.

Caution

Do not rely solely on pulse oximetry; a drop in SpO2 is a late sign of hypoventilation. Sedation always precedes respiratory depression, so a sedated patient requires immediate assessment of their respiratory status.

핵심 개념

Merci NCLEX-RN Question Bank 3,445 문제 · 로그인 없이 바로 볼 수 있어요

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