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학습 자료 둘러보기 →Any jaundice appearing within the first 24 hours of life is pathological until proven otherwise. This is a medical emergency often linked to hemolytic disease (e.g., ABO or Rh incompatibility).
The presence of lethargy, poor feeding, or hypotonia alongside jaundice is a critical red flag. These are early signs of bilirubin-induced neurological dysfunction (BIND), indicating that unconjugated bilirubin may be crossing the blood-brain barrier.
Do not wait for jaundice to spread to the trunk or for a high bilirubin level to act. The combination of early onset and neurological signs requires immediate intervention, including intensive phototherapy or exchange transfusion.
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