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학습 자료 둘러보기 →For a child with a serious CA-MRSA infection, 48 hours of IV vancomycin is typically insufficient to confirm full clinical resolution. The primary intervention is to continue the current therapy and monitor for both clinical improvement (e.g., reduced erythema, fever) and adverse effects (e.g., nephrotoxicity, red man syndrome).
Maintain strict contact precautions for the duration of the active, draining wound. The decision to transition to oral antibiotics requires clear evidence of clinical stability, often after at least 5-7 days of IV therapy and in consultation with infectious disease specialists.
Never discontinue isolation or plan for discharge prematurely based solely on a 48-hour antibiotic course. Vancomycin dosing must be guided by therapeutic drug monitoring of trough levels to ensure efficacy and minimize toxicity.
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