A 12-year-old child with aplastic anemia is admitted to the … | 마이메르시 MyMerci
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Aplastic anemia

A 12-year-old child with aplastic anemia is admitted to the pediatric unit. Which nursing intervention should be the highest priority?

The nurse is caring for a pediatric patient with aplastic anemia who requires immediate attention to prevent life-threatening complications.
해설
Aplastic anemia involves bone marrow failure resulting in pancytopenia (decreased red blood cells, white blood cells, and platelets). The highest priority is preventing infection due to neutropenia, as infections can be life-threatening in immunocompromised patients.

Aplastic anemia is a serious hematologic condition caused by bone marrow failure, characterized by pancytopenia (a marked decrease in red blood cells, white blood cells, and platelets). In pediatric patients, this disease can pose an immediate life threat, requiring high-priority nursing interventions.

Pathophysiologically, damage to or destruction of hematopoietic stem cells in the bone marrow leads to inadequate blood cell production. This can result from various causes such as viral infections, drugs, chemicals, radiation exposure, or autoimmune processes. The resulting pancytopenia causes multiple clinical problems, but the most immediate life threat is severe neutropenia.

Neutropenia is defined as an absolute neutrophil count below 1,500/μL (below 500/μL in severe cases) and dramatically increases the risk of serious bacterial, fungal, and viral infections. Children with aplastic anemia often have neutrophil counts of 200/μL or less, placing them at extremely high risk for life-threatening sepsis. Unlike healthy individuals, these patients may not show a typical inflammatory response to infection, so common signs like fever, purulent discharge, or localized inflammation may be absent.

Implementing strict neutropenic precautions is the top-priority nursing intervention because preventing infection directly addresses the most immediate threat to patient survival. These precautions include placing the patient in a positive-pressure private room when possible, enforcing strict hand hygiene for all visitors and staff, using personal protective equipment, restricting live flowers and plants, ensuring all food is thoroughly cooked, and monitoring for subtle signs of infection such as changes in mental status, unexplained fatigue, or slight temperature elevations.

Since these patients may not show typical infection symptoms, nursing assessments must be comprehensive and frequent. Early recognition and prompt treatment of infection are critical for survival. This priority intervention directly impacts patient outcomes and aligns with the NCLEX-RN emphasis on safety and infection control in vulnerable populations.
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