In a child with sickle cell disease presenting with vaso-occlusive crisis, severe bone and extremity pain is the hallmark symptom. The priority intervention is pain management with prescribed analgesics to relieve suffering and prevent secondary complications such as splinting and hypoventilation.
While hydration, warm compresses, and oxygen therapy (if hypoxemic) are important supportive measures, they are secondary to pharmacologic pain relief when no signs of respiratory compromise are present.
Assess for signs of acute chest syndrome (ACS) such as hypoxemia, respiratory distress, or fever. If respiratory compromise is present, oxygen therapy becomes the priority. In the absence of such findings, pain management is the immediate priority.
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