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학습 자료 둘러보기 →The classic presentation is simultaneous hemoptysis and hematuria, known as pulmonary-renal syndrome. This reflects autoantibody attack on type IV collagen in both alveolar and glomerular basement membranes.
Suspect Goodpasture's in a young male with hemoptysis, dyspnea, and hematuria with rising creatinine. Confirm with anti-GBM antibody serology and renal biopsy showing linear IgG deposition.
Rapid deterioration is common. Monitor for massive hemoptysis and acute kidney injury. Early plasmapheresis and immunosuppression are critical to prevent irreversible organ damage.
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