The trauma patient showed signs of _____, a condition where … | 마이메르시 MyMerci
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Diseases of the blood and blood-forming organs
문제

The trauma patient showed signs of _____, a condition where blood clots start forming throughout the bloodstream.

해설
Coagulopathy, specifically disseminated intravascular coagulation (DIC), is a serious condition where blood clots form throughout the body's blood vessels, leading to organ damage. Simultaneously, clotting factors are depleted, causing bleeding. Common causes include severe trauma, sepsis, and obstetric complications. It requires immediate medical intervention to prevent organ failure.
같은 주제 다음 문제CBC shows severe ______ with hemoglobin of 6.2 g/dL, requiring immediate transfusion.

임상 시나리오

DIC (Disseminated Intravascular Coagulation):
- Pathophysiology: Widespread activation of blood clotting
- Clinical features: Bleeding, organ failure, thrombosis
- Laboratory findings: Low platelets, elevated D-dimer, prolonged PT/PTT
- Triggers: Trauma, infection, cancer, obstetric complications
- Treatment: Treat underlying cause, supportive care, blood products

Coagulation Cascade:
- Intrinsic pathway: Factor XII activation
- Extrinsic pathway: Tissue factor exposure
- Common pathway: Thrombin formation
- Final step: Fibrin clot formation

Clotting Factors:
- Factor I: Fibrinogen
- Factor II: Prothrombin
- Factor VII: Proconvertin
- Factor VIII: Antihemophilic factor
- Factor IX: Christmas factor
- Factor X: Stuart-Prower factor

Coagulation Tests:
- PT: Extrinsic pathway
- PTT: Intrinsic pathway
- INR: Standardized PT
- D-dimer: Fibrin breakdown
- Fibrinogen level: Clotting capacity

핵심 개념

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