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審查達托黴素治療趨勢，並確定優先解釋和行動。

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Time	Data
Before therapy	CPK 88 U/L; creatinine clearance 46 mL/min; no muscle pain; simvastatin listed as a home medication肌酸磷化酶（CPK） 88 U/L；肌酸酐清除率 46 mL/min；無肌肉疼痛；辛伐他汀列為居家藥物
Day 3	CPK 310 U/L; mild thigh aching; creatinine clearance 42 mL/min肌酸磷化酶（CPK） 310 U/L；輕微大腿痠痛；肌酸酐清除率 42 mL/min
Day 5	CPK 1480 U/L; new proximal weakness and dark urine; next dose due in 1 hour肌酸磷化酶（CPK） 1480 U/L；新的近端無力和深色尿液；下一劑藥物預計在 1 小時後給予

Q1. Which complication is most likely?最可能發生哪種併發症？

Expected antimicrobial response預期的抗菌反應 Daptomycin-associated myopathy with possible rhabdomyolysis達托黴素相關肌病伴可能橫紋肌溶解症 Isolated dehydration without drug involvement單純脫水，與藥物無關

Q2. Which action is the priority?哪項行動是優先事項？

Give the next dose and recheck CPK next month給予下一劑藥物並於下個月重新檢查肌酸磷化酶（CPK） Use daptomycin to treat a new pneumonia使用達托黴素治療新的肺炎 Hold the dose and notify the authorized team for urgent toxicity and regimen review暫停給藥並通知授權團隊進行緊急毒性及治療方案審查

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