# Situation: A nurse works in the pediatric ward and the adolescent health clinic of a city hospital during the rainy season. A 9-year-old admitted with dengue is on day 5 of illness. The nurse compares today's findings with those of the previous day: Temperature: 39.2 °C → 37.0 °C Hematocrit: 38% → 47% Platelet count: 110,000/µL → 42,000/µL Pulse: 104/min → 132/min Blood pressure: 100/68 mmHg → 98/84 mmHg Capillary refill: 2 seconds → 4 seconds He is restless but alert, and has no bleeding. Following DOH dengue management guidelines, which action should the nurse take FIRST?

> source: MyMerci (mymerci.kr)  
> url: https://mymerci.kr/pages/nclex_q.php?qn_id=629553  
> language: ko  
> subject: Nursing Practice II — Maternal and Child Health Nursing

## 문제

Situation: A nurse works in the pediatric ward and the adolescent health clinic of a city hospital during the rainy season.

A 9-year-old admitted with dengue is on day 5 of illness. The nurse compares today's findings with those of the previous day:
Temperature: 39.2 °C → 37.0 °C
Hematocrit: 38% → 47%
Platelet count: 110,000/µL → 42,000/µL
Pulse: 104/min → 132/min
Blood pressure: 100/68 mmHg → 98/84 mmHg
Capillary refill: 2 seconds → 4 seconds
He is restless but alert, and has no bleeding. Following DOH dengue management guidelines, which action should the nurse take FIRST?

## 보기

1. Give paracetamol for his body aches as ordered
2. Send blood for a repeat hematocrit and platelet count
3. Start the ordered isotonic crystalloid fluid bolus **✔ 정답**
4. Prepare the ordered platelet concentrate transfusion

**정답: 3**

## 해설

The fever has broken on day 5, the hematocrit is rising while platelets fall, and tachycardia, delayed capillary refill, restlessness, and a narrowing gap between systolic and diastolic pressure show plasma leakage with circulatory compromise in the critical phase. Isotonic crystalloid resuscitation, titrated to vital signs, hematocrit, and urine output, comes first. Repeat laboratory tests guide later fluid rates, platelet transfusion is reserved for significant bleeding, and paracetamol is not the priority.

## 심화 해설

Clinical context

A 9-year-old with dengue on day 5 of illness shows a classic transition into the critical phase. The fever defervesces, but that is not reassuring. The comparison between yesterday and today reveals rising hematocrit with falling platelets, tachycardia, narrowed pulse pressure, delayed capillary refill, and restlessness—all signs of plasma leakage with early circulatory compromise.

Why the correct answer is the isotonic crystalloid bolus

In dengue, the critical phase typically begins around day 3–7 of illness, often as the fever subsides. The underlying problem is a transient, generalized increase in capillary permeability. Plasma leaks out of the intravascular space into interstitial compartments, causing hemoconcentration and intravascular volume depletion. The hematocrit rising from 38% to 47% is a direct reflection of this plasma loss, not of red cell gain. The platelet drop from 110,000/µL to 42,000/µL is expected in the critical phase and does not by itself require platelet transfusion.

The hemodynamic findings confirm that the leak is now compromising perfusion. The pulse has risen from 104/min to 132/min, capillary refill has slowed from 2 seconds to 4 seconds, and the pulse pressure has narrowed from 32 mmHg to 14 mmHg. Narrowing pulse pressure is an early and sensitive indicator of reduced stroke volume in dengue shock. Restlessness in this setting reflects inadequate cerebral perfusion, not simply anxiety.

Key point! In the critical phase of dengue, the priority is to restore intravascular volume with isotonic crystalloid. The WHO and DOH guidelines consistently recommend crystalloids as the initial fluid of choice for dengue with warning signs or compensated shock. Fluid resuscitation must be titrated to clinical response—vital signs, hematocrit trend, and urine output—not given as a fixed one-time order.

Why the other options are not the first action

| Option | Why it is not first |
| --- | --- |
| 1. Paracetamol for body aches | Paracetamol is appropriate for fever and pain in dengue, but this child’s fever has already subsided. The immediate threat is hypoperfusion from plasma leakage, not discomfort. Giving paracetamol first would delay volume resuscitation. |
| 2. Repeat hematocrit and platelet count | Serial hematocrit is essential for monitoring dengue, but it is a diagnostic and monitoring step, not a therapeutic intervention. In a child with signs of compensated shock, obtaining another lab sample before starting fluids wastes critical time. The hematocrit trend is already known and supports the diagnosis of plasma leakage. |
| 4. Platelet concentrate transfusion | Prophylactic platelet transfusion is not indicated in dengue regardless of how low the count falls. Platelet transfusion is reserved for significant clinical bleeding, which this child does not have. Transfusing platelets without bleeding does not improve outcomes and exposes the child to unnecessary risks. |

Pathophysiology of the critical phase

Dengue illness has three phases: febrile, critical, and recovery. The critical phase occurs around defervescence, when capillary permeability peaks. The mechanism involves endothelial dysfunction driven by viral factors and host inflammatory mediators. Plasma leaks through widened endothelial junctions, reducing circulating volume. The body compensates initially with tachycardia and peripheral vasoconstriction, which is why blood pressure may remain near normal while pulse pressure narrows and capillary refill prolongs.

The hematocrit is a surrogate marker for plasma leakage severity. A rising hematocrit means hemoconcentration—the red cells are becoming more concentrated because the plasma component is escaping. A falling hematocrit after fluid resuscitation suggests hemodilution and can indicate that leakage is resolving or that fluids are being retained. This is why hematocrit is monitored serially during the critical phase, but it does not replace the need for immediate clinical intervention when shock is present.

Fluid management principles

For a child with compensated dengue shock, the initial approach is an isotonic crystalloid bolus, typically 10–20 mL/kg over 1 hour, with reassessment. The goal is to improve perfusion without causing fluid overload. Over-resuscitation is dangerous because the leaked plasma will be reabsorbed during the recovery phase, and excess fluid can lead to pulmonary edema or congestive heart failure.

Watch out! A normal or only slightly decreased systolic blood pressure does not rule out shock. In children, compensatory mechanisms can maintain systolic pressure until late in the course. Narrowing pulse pressure, tachycardia, delayed capillary refill, and altered mental status are earlier and more reliable indicators of compensated shock than hypotension alone.

Clinical reasoning for the nurse

The nurse should recognize that this child is in the critical phase with compensated shock. The first action is to initiate the ordered isotonic crystalloid bolus and monitor the response closely. Repeat hematocrit and platelet counts are useful after the bolus to guide subsequent fluid rates. Platelet transfusion is not indicated without bleeding. Paracetamol is not the priority when perfusion is compromised.

Fluid resuscitation in the critical phase of dengue is the cornerstone of management and must begin as soon as compensated shock is recognized. The decision to give fluids is clinical, based on hemodynamic signs and hematocrit trend, not on waiting for additional laboratory confirmation.

## 임상 시나리오

Dengue Critical Phase Recognition and Fluid ResuscitationDOH-aligned priorities when fever breaks but perfusion worsens
Day 5 defervescence is not reassuring. Rising hematocrit from 38% to 47% with falling platelets marks the critical phase of plasma leakage.

Early shock signs include narrowing pulse pressure (32 to 14 mmHg), tachycardia, and delayed capillary refill (4 seconds). These indicate reduced stroke volume and require immediate isotonic crystalloid bolus.

CautionPlatelet transfusion is reserved for significant bleeding, not for thrombocytopenia alone. Repeat labs guide later fluid titration but do not replace the first bolus.

## 핵심 개념

- **Critical phase** — Period around day 3-7 of dengue when fever subsides and plasma leakage can cause shock.
- **Plasma leakage** — Increased capillary permeability causing fluid shift from intravascular to interstitial space, seen as rising hematocrit.
- **Pulse pressure** — Difference between systolic and diastolic BP; narrowing indicates reduced stroke volume in dengue shock.
- **Hemoconcentration** — Elevated hematocrit due to plasma loss, not increased red cell mass.
- **Isotonic crystalloid** — First-line fluid for dengue with circulatory compromise, titrated to vitals, Hct, and urine output.

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