# A client who could become pregnant is prescribed misoprostol to reduce NSAID-induced gastric-ulcer risk. Which actions are appropriate? Select exactly 4 responses.

> source: MyMerci (mymerci.kr)  
> url: https://mymerci.kr/pages/nclex_q.php?qn_id=602996&lang=en  
> language: en  
> subject: Adverse Effects/Contraindications/Interactions  
> category: PPT

## Question

A client who could become pregnant is prescribed misoprostol to reduce NSAID-induced gastric-ulcer risk. Which actions are appropriate? Select exactly 4 responses.

Select exactly 4 responses.

1

Verify that the client is not pregnant before therapy begins.

2

Instruct the client to contact the prescriber promptly if pregnancy is suspected.

3

Confirm use of effective contraception during misoprostol therapy.

4

Advise stopping contraception as soon as the first misoprostol dose is taken.

5

Teach that misoprostol is safe to share with any pregnant person who has stomach pain.

6

Explain that the drug can cause abortion, premature birth, or fetal harm if pregnancy occurs.

## Explanation

For NSAID-ulcer prevention, misoprostol must not be used during pregnancy. The client needs pregnancy exclusion, effective contraception, explicit reproductive-risk counseling, and prompt reporting of suspected pregnancy.

## In-depth explanation

Quick answer
Prevent pregnancy exposure to misoprostol used for ulcer prophylaxis.

Why this is correct
Misoprostol can cause uterine contractions, abortion, premature birth, uterine rupture, or fetal harm. It must never be shared.

Easy analogy or mental picture
Use a closed medication-safety loop: identify the exposure, connect the new findings, interrupt further harm, support physiology, and verify the response over time.

Memory hook
Exposure, interaction, toxicity pattern, immediate action, serial reassessment.

NCLEX decision rule
Choose the action that reduces the most immediate medication-related risk while preserving monitoring and escalation.

Why the other choices are wrong
Options that continue the exposure, treat only one symptom, or delay reassessment leave the toxic process active.References
1DailyMed: CYTOTEC (misoprostol)Pregnancy contraindication for NSAID-ulcer prevention, uterine effects, contraception, and patient counseling

## Clinical scenario

Medication safety review
Verify the indication, route, interacting medicines, current respiratory and gastrointestinal findings, authorized action, and measurable follow-up.

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