# A nurse is reviewing several insulin orders. For each cue, drag it to the insulin product that best matches the clinical situation.

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> url: https://mymerci.kr/pages/nclex_q.php?qn_id=568364&lang=en  
> language: en  
> subject: Medication Administration  
> category: PPT

## Question

A nurse is reviewing several insulin orders. For each cue, drag it to the insulin product that best matches the clinical situation.

**1.** Administer 15 minutes before a meal to cover postprandial glucose rise

Select a category
NPH insulin
Insulin lispro
Insulin glargine

**2.** Use for correction of hyperglycemia at bedtime when no food is planned

Select a category
NPH insulin
Insulin lispro
Insulin glargine

**3.** Give once daily at the same time each evening as basal coverage

Select a category
NPH insulin
Insulin lispro
Insulin glargine

**4.** Do not mix with other insulins in the same syringe

Select a category
NPH insulin
Insulin lispro
Insulin glargine

**5.** Clear, colorless solution that does not require resuspension

Select a category
NPH insulin
Insulin lispro
Insulin glargine

**6.** Cloudy suspension that requires gentle rolling before administration

Select a category
NPH insulin
Insulin lispro
Insulin glargine

**7.** Administer twice daily to provide basal coverage with peaks

Select a category
NPH insulin
Insulin lispro
Insulin glargine

## Explanation

The cues describe clinical scenarios that require matching insulin products to their onset, peak, duration, appearance, and administration requirements. Lispro is a rapid-acting insulin used to cover mealtime glucose excursions. Regular insulin is a short-acting insulin that can be given intravenously in acute settings. NPH is an intermediate-acting insulin that is cloudy and requires gentle mixing before administration. Glargine is a long-acting basal insulin that is clear and should not be mixed with other insulins.

## In-depth explanation

Quick answer
The correct matches are based on the pharmacological profiles and clinical administration requirements of each insulin product.

Why this is correct
Each cue describes a clinical situation that aligns with the characteristics of a specific insulin product. For example, a clear basal insulin given once daily without mixing matches glargine, while a cloudy insulin requiring resuspension matches NPH.

Clinical picture
Insulin products differ in onset, peak, duration, appearance, and compatibility. Rapid-acting insulins like lispro are used for prandial coverage. Short-acting regular insulin can be given intravenously. Intermediate-acting NPH is a cloudy suspension. Long-acting glargine is clear and cannot be mixed with other insulins.

Memory hook
Remember the mnemonic: 'Clear before cloudy' for drawing up insulins, and 'Glargine is clear and alone' for administration. NPH is the only cloudy insulin among the common products.

NCLEX decision rule
Match insulin products to their clinical use: rapid-acting for meals, short-acting for IV use, intermediate-acting for twice-daily basal coverage with mixing, and long-acting for once-daily basal without mixing.

Why the alternatives are wrong
Incorrect matches would result from confusing onset times (e.g., using lispro for basal coverage), mixing incompatible insulins (e.g., glargine with regular), or failing to recognize that NPH requires resuspension.

Sources
1NCSBN 2026 NCLEX-RN Test Plan
2WHO: types and modes of action of insulin
3DailyMed: insulin glargine prescribing information

## Clinical scenario

Insulin safety check
The nurse verifies the current prescription, glucose result, nutrition plan, and facility protocol before administration.

## Key concepts

- **Rapid-acting insulin** — Insulin with onset of 10-30 minutes, peak of 30-90 minutes, and duration of 3-5 hours, used to cover mealtime glucose excursions.
- **Short-acting insulin** — Insulin with onset of 30-60 minutes, peak of 2-4 hours, and duration of 5-8 hours, can be given intravenously under protocol.
- **Intermediate-acting insulin** — Insulin with onset of 1-2 hours, peak of 4-12 hours, and duration of 18-24 hours, appears cloudy and requires gentle mixing.

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