# A client with a nasogastric tube is receiving continuous enteral nutrition. The nurse must administer immediate-release metoprolol tablets, an enteric-coated aspirin tablet, and phenytoin suspension, which is known to bind with enteral formula and reduce absorption. Which actions should the nurse take? Select all that apply.

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> language: en  
> subject: Adverse Effects/Contraindications/Interactions  
> category: PPT

## Question

A client with a nasogastric tube is receiving continuous enteral nutrition. The nurse must administer immediate-release metoprolol tablets, an enteric-coated aspirin tablet, and phenytoin suspension, which is known to bind with enteral formula and reduce absorption. Which actions should the nurse take? Select all that apply.

1

Crush the enteric-coated aspirin tablet and dissolve it in warm water before instilling it through the tube.

2

Interrupt the continuous enteral feeding for the period needed to allow phenytoin absorption, then resume feeding afterward.

3

Crush the metoprolol tablet and mix it with the phenytoin suspension in the same syringe for one instillation.

4

Add the phenytoin suspension directly into the enteral feeding bag so it infuses along with the formula.

5

Flush the nasogastric tube with water before and after administering each medication separately.

6

Contact the prescriber to request a non-enteric-coated or liquid form of the aspirin for tube administration.

## Explanation

Safe enteral medication administration requires evaluating each drug individually for compatibility, absorption, and interaction with tube feeding rather than treating all medications the same way. Enteric-coated products cannot be crushed because doing so destroys their protective release mechanism, so the nurse should seek an alternative formulation instead. Phenytoin requires a feeding interruption because the enteral formula binds the drug and reduces absorption, unlike medications without such interactions. Medications should never be combined in one syringe or added directly to a feeding bag, since this risks incompatibility, occlusion, and unpredictable dosing. Flushing the tube before and after each medication, given separately, maintains patency and prevents drug-formula or drug-drug interactions, making it a consistently appropriate nursing action in this scenario.

## In-depth explanation

Correct Answer
Choices 2, 5, 6

Clinical Reasoning
Safe enteral medication administration requires evaluating each drug individually for compatibility, absorption, and interaction with tube feeding rather than treating all medications the same way. Enteric-coated products cannot be crushed because doing so destroys their protective release mechanism, so the nurse should seek an alternative formulation instead. Phenytoin requires a feeding interruption because the enteral formula binds the drug and reduces absorption, unlike medications without such interactions. Medications should never be combined in one syringe or added directly to a feeding bag, since this risks incompatibility, occlusion, and unpredictable dosing. Flushing the tube before and after each medication, given separately, maintains patency and prevents drug-formula or drug-drug interactions, making it a consistently appropriate nursing action in this scenario.

Option Review

- Incorrect — Enteric-coated tablets are formulated to resist stomach acid and release medication in the intestine, so crushing destroys this protective coating and alters absorption and safety.

- Correct — Phenytoin binds with enteral formula components, so holding the feeding before and after the dose protects absorption and ensures the client receives an effective dose.

- Incorrect — Combining two different medications in one syringe risks physical incompatibility, tube occlusion, and altered absorption, so each drug should be prepared and given separately.

- Incorrect — Instilling medication directly into the feeding bag exposes the drug to prolonged contact with formula, risking degradation, incompatibility, and inaccurate dosing over time.

- Correct — Flushing before and after each medication clears the tube, prevents drug-formula interaction, and reduces the risk of occlusion, supporting safe individual administration.

- Correct — Because the enteric coating cannot be crushed safely, the prescriber should be consulted to obtain an alternative formulation suitable for enteral tube delivery.

Sources
12026 NCLEX-RN Test Plan
2ASPEN Safe Practices for Enteral Nutrition Therapy

## Clinical scenario

A client with a nasogastric tube receiving continuous enteral nutrition is due for immediate-release metoprolol, an enteric-coated aspirin tablet, and phenytoin suspension, which is known to bind with enteral formula and reduce absorption.

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