# A nurse is caring for a patient who has been prescribed warfarin therapy. Which assessment finding would require the nurse to take immediate action?

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> subject: Next Gen NCLEX

## 문제

A nurse is caring for a patient who has been prescribed warfarin therapy. Which assessment finding would require the nurse to take immediate action?

## 보기

1. Black, tarry stools and a hemoglobin level of 7.2 g/dL **✔ 정답**
2. INR level of 2.8 with no signs of bleeding
3. Bruising on the arms and legs from minor trauma
4. Gum bleeding when brushing teeth

**정답: 1**

## 해설

Black, tarry stools with low hemoglobin indicate active GI bleeding, a life-threatening complication of warfarin requiring immediate action. Other findings are less urgent.

## 심화 해설

Clinical Priority Analysis

The correct answer is option 1: Black, tarry stools and a hemoglobin level of 7.2 g/dL. This combination of findings signals an active, potentially life-threatening gastrointestinal (GI) hemorrhage requiring immediate nursing action.

Pathophysiology and Clinical Reasoning

Warfarin exerts its anticoagulant effect by inhibiting vitamin K epoxide reductase, thereby reducing the synthesis of functional clotting factors II, VII, IX, and X. A major adverse effect of this therapy is bleeding, with the GI tract being a common site. The presence of melena (black, tarry stools) indicates that blood has been exposed to digestive enzymes and gastric acid, confirming an upper GI source of bleeding [1]. A hemoglobin of 7.2 g/dL represents a significant drop from normal values (typically 12-16 g/dL for females and 14-18 g/dL for males), indicating a substantial loss of red blood cell mass. This level is below the commonly accepted transfusion threshold of 7-8 g/dL in many clinical guidelines, signifying that the patient's oxygen-carrying capacity is critically compromised. The combination of ongoing blood loss and severe anemia can rapidly progress to hypovolemic shock, as evidenced by case reports where patients with warfarin-associated upper GI bleeding presented with hypotension and tachycardia alongside a hemoglobin of 6.8 g/dL [1]. This scenario demands immediate assessment of hemodynamic stability, notification of the provider, preparation for potential blood transfusion, and administration of vitamin K or other reversal agents as ordered.

Analysis of Incorrect Options

- Option 2: An INR of 2.8 without bleeding signs is a therapeutic level for many indications, such as atrial fibrillation or venous thromboembolism, where the target range is typically 2.0-3.0. While this requires monitoring, it does not represent an immediate threat in the absence of active hemorrhage.

- Option 3: Bruising (ecchymosis) on the extremities from minor trauma is a common and expected sign of anticoagulation. It indicates a heightened bleeding tendency but is not an acute, life-threatening event. The nurse's action would be patient education on safety and monitoring, not an emergency response.

- Option 4: Gum bleeding when brushing teeth is a minor mucocutaneous bleed. While it warrants evaluation of the INR and reinforcement of gentle oral care, it does not pose the immediate risk of hemodynamic instability that a major GI hemorrhage does.

NCLEX-RN Application: Prioritization and Triage

This question tests the critical nursing skill of prioritizing care using a framework like the ABCs (Airway, Breathing, Circulation) and the concept of "acute versus chronic." Active GI bleeding with a critically low hemoglobin directly threatens the "C" (Circulation) component, placing the patient at high risk for decompensation. Research confirms that non-variceal upper GI bleeding in patients on antithrombotic therapy remains a major clinical emergency with significant morbidity . The nurse must recognize that melena is not an isolated symptom but a marker of a dynamic, ongoing process. Furthermore, the risk of such bleeding is a well-documented complication of oral anticoagulation, and its management is a high-priority nursing intervention . A non-traumatic muscle hematoma, while serious, illustrates that bleeding can occur in various locations; however, a GI bleed with a hemoglobin of 7.2 g/dL represents a more immediate threat to circulating volume and perfusion than a contained hematoma or superficial bleeding . The nurse's immediate actions must focus on stabilizing the patient's circulatory status.References (research sources)

- [1]Persistent Anticoagulation and Severe Upper Gastrointestinal Bleeding in a Patient With Factor V Leiden: A Case of the Warfarin Reservoir Phenomenon.Case reportKammawal Y. (2025) · DOI: 10.7759/cureus.91638

## 임상 시나리오

Warfarin-Induced GI Bleed: Emergency RecognitionPrioritizing Active Hemorrhage with Hemodynamic Compromise
The combination of melena and a critically low hemoglobin of 7.2 g/dL confirms an active, major upper GI bleed. This level is below the common transfusion threshold of 7-8 g/dL and indicates severely compromised oxygen-carrying capacity.

Immediate nursing actions include assessing for signs of hypovolemic shock such as hypotension and tachycardia, ensuring large-bore IV access, and preparing for urgent blood transfusion. The provider must be notified immediately.

CautionDo not confuse a supratherapeutic INR alone with an emergency. An INR of 2.8 is often therapeutic. The presence of active bleeding with hemodynamic instability, not just the lab value, dictates the urgency.

## 핵심 개념

- **Melena** — Black, tarry stools caused by the digestion of blood in the GI tract, indicating an upper gastrointestinal bleed.
- **Warfarin** — An oral anticoagulant that inhibits vitamin K-dependent clotting factors (II, VII, IX, X) to prevent thromboembolism.
- **Hemoglobin** — A protein in red blood cells that carries oxygen; a level of 7.2 g/dL indicates severe anemia and compromised oxygen delivery.
- **INR (International Normalized Ratio)** — A laboratory test used to monitor warfarin therapy and measure the extrinsic pathway of coagulation.
- **Hypovolemic Shock** — A life-threatening condition resulting from rapid fluid or blood loss, leading to inadequate tissue perfusion.

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