# A 3-year-old child with neuroblastoma is receiving chemotherapy and has developed severe mucositis. The child is refusing to eat and has lost 2 kg over the past week. Which nursing intervention should be the priority?

> source: MyMerci (mymerci.kr)  
> url: https://mymerci.kr/pages/nclex_q.php?qn_id=542214  
> language: ko  
> subject: Child Health

## 문제

A 3-year-old child with neuroblastoma is receiving chemotherapy and has developed severe mucositis. The child is refusing to eat and has lost 2 kg over the past week. Which nursing intervention should be the priority?

The nurse is caring for a toddler with neuroblastoma who is experiencing treatment-related complications.

## 보기

1. Encourage the child to eat favorite foods and provide nutritional supplements
2. Apply topical anesthetic gel to the oral lesions before meals
3. Collaborate with the healthcare team to initiate parenteral nutrition **✔ 정답**
4. Provide frequent oral care with soft-bristled toothbrush and mild mouthwash

**정답: 3**

## 해설

Severe mucositis with significant weight loss and food refusal requires immediate nutritional intervention to prevent malnutrition and support healing.

Neuroblastoma is the most common extracranial solid tumor in children under 5 years of age. Children with neuroblastoma are at high risk of developing stomatitis when receiving chemotherapy. Stomatitis refers to inflammation and ulceration of the mucosa lining the mouth and gastrointestinal tract.

In this case, the child developed severe stomatitis and showed a weight loss of 2 kg over one week. This is a rapid weight loss that represents a significant percentage of body weight for a 3-year-old child. This rapid weight loss and food refusal indicate that the child's nutritional status is severely compromised.

The priority nursing intervention must address the immediate threat to the child's nutritional status and overall health. Parenteral nutrition (PN) delivers essential nutrients directly into the bloodstream, bypassing the damaged gastrointestinal tract. This intervention is crucial when oral intake is inadequate or impossible due to severe stomatitis.

Parenteral nutrition maintains nutritional status, supports immune function, promotes mucosal healing, and prevents further weight loss and malnutrition-related complications. Collaboration with the healthcare team is essential to initiate parenteral nutrition, as it requires a physician's order, dietitian consultation, and pharmacy preparation of the solution.

While other supportive measures are also important, addressing the immediate nutritional crisis is the priority. The child's food refusal and significant weight loss indicate that oral interventions alone are insufficient to meet nutritional needs during this critical period of treatment.

## 심화 해설

Understanding the Priority: Severe Mucositis and Nutritional Decline

When a child undergoing chemotherapy develops severe mucositis and experiences significant weight loss, the clinical picture shifts from a comfort-care focus to a medical emergency related to nutritional status. The key detail in this scenario is the weight loss of 2 kg in one week. For a 3-year-old toddler, this represents a substantial percentage of total body weight and signals acute malnutrition. The oral mucosa is so severely ulcerated that the child has completely ceased oral intake. In this context, the gastrointestinal tract is non-functional for feeding, and the priority becomes bypassing it entirely to deliver essential nutrients and prevent further catabolism.

Why Parenteral Nutrition is the Priority

The correct intervention is to collaborate with the healthcare team to initiate parenteral nutrition. The rationale is rooted in the pathophysiology of cancer cachexia and the limitations of other interventions when mucositis is severe. Chemotherapy targets rapidly dividing cells, which includes not only cancer cells but also the epithelial cells lining the oral cavity and entire gastrointestinal tract. This leads to a breakdown of the mucosal barrier, resulting in the erythema and ulceration characteristic of oral mucositis (OM) [1]. When OM is graded as severe using tools like the World Health Organization (WHO) Mucositis Grading System, the pain is so intense that oral intake becomes impossible [2]. Attempting to encourage oral feeding at this stage is not only ineffective but can increase the child's distress and pain. Similarly, while topical anesthetics can provide temporary relief for mild to moderate mucositis, they are insufficient when the child has already stopped eating entirely and is in a state of rapid nutritional decline. The immediate threat to the child's life and ability to tolerate ongoing cancer treatment is starvation, making the provision of nutrition via an alternative route the absolute priority.

Why Other Options Are Not the Priority

- Encouraging favorite foods and supplements: This intervention is appropriate for a child with a poor appetite or mild oral discomfort but is contraindicated as a primary strategy for severe mucositis with complete food refusal. The underlying problem is not a lack of appealing food choices but intense, ulcerative pain that makes any oral intake agonizing . Pushing oral intake can create a negative association with eating and does not address the urgent caloric and protein deficit.

- Applying topical anesthetic gel: While managing pain is a critical component of mucositis care, this is a supportive, not a primary, intervention when the child is already malnourished. Topical agents provide short-term, localized numbness that may facilitate oral care or a small amount of intake, but they do not solve the problem of a child who has already lost a dangerous amount of weight due to complete oral aversion [1]. Pain control should be implemented systemically and alongside nutritional support, not as the sole solution.

- Providing frequent oral care: Meticulous oral hygiene is a cornerstone of preventing and managing OM. Using a soft-bristled toothbrush and mild mouthwash helps reduce the microbial load on ulcerated tissues, potentially decreasing the risk of secondary infection and sepsis, which are major concerns in immunocompromised patients [3,4]. However, oral care is a supportive measure that prevents complications; it does not address the immediate, life-threatening nutritional deficit. In the hierarchy of needs for this child, delivering life-sustaining calories and nutrients takes precedence over hygiene, though both are essential components of the overall care plan.

The initiation of parenteral nutrition directly addresses the most acute threat: the catabolic state resulting from severe, chemotherapy-induced mucositis that has completely precluded oral intake. This intervention stabilizes the child's nutritional status, prevents further weight loss, and ensures they have the metabolic reserves necessary to heal and continue with their essential cancer treatment .References (research sources)

- [1]Use of topical Vitamin E in oral mucositis in patients undergoing oncology treatment. Scoping review.Research articleSanmartín-Barragáns V, Vázquez-Rico M, Camolesi GC, Prado-Pena IB, García-Carnicero T, Pérez-Sayáns M, Blanco-Carrión A, Gándara-Vila P. (2026) · DOI: 10.4317/medoral.27790

- [2]Oral manifestations of pediatric cancer patients receiving chemotherapy and dental awareness among their parents-a cross-sectional study.Research articleAl-Sayed AM, El-Tawil SB, Madney Y, Yousry YM. (2026) · DOI: 10.1186/s12903-026-07983-7

## 임상 시나리오

Managing Severe Mucositis & Nutritional Failure in Pediatric OncologyWhen oral intake ceases, prioritize parenteral nutrition.
Severe mucositis (WHO Grade 3-4) renders the GI tract non-functional. A weight loss of 2 kg in a toddler signals acute malnutrition and requires immediate intervention.

The priority is to collaborate with the team to initiate parenteral nutrition. This bypasses the damaged mucosa to deliver essential nutrients and prevent cancer cachexia.

CautionTopical anesthetics and oral care are comfort and supportive measures only. Do not delay nutritional support when significant weight loss is present, as oral intake is not feasible.

## 핵심 개념

- **Oral Mucositis** — Inflammation and ulceration of the oral mucosa, a common side effect of chemotherapy due to its effect on rapidly dividing epithelial cells.
- **Parenteral Nutrition** — Intravenous administration of nutrients, bypassing the gastrointestinal tract, indicated when the gut is non-functional or inaccessible.
- **Cancer Cachexia** — A multifactorial syndrome characterized by progressive weight loss, muscle wasting, and anorexia, driven by metabolic changes from cancer and its treatment.
- **WHO Mucositis Grading** — A scale for assessing mucositis severity; Grade 3-4 involves severe pain and inability to swallow solids or liquids, requiring nutritional support.
- **Pediatric Weight Loss Significance** — A loss of 2 kg in a toddler represents a significant percentage of body weight, indicating acute malnutrition and a medical emergency.

## 같은 주제 문제

- [A 3-year-old child is admitted to the pediatric oncology unit with a suspected neuroblasto…](https://mymerci.kr/pages/nclex_q.php?qn_id=542207)
- [A 3-year-old child is admitted to the pediatric unit with suspected neuroblastoma. Which a…](https://mymerci.kr/pages/nclex_q.php?qn_id=542208)
- [A 3-year-old child is admitted to the pediatric unit with suspected neuroblastoma. Which a…](https://mymerci.kr/pages/nclex_q.php?qn_id=542209)
- [A 3-year-old child is admitted to the pediatric oncology unit with a suspected neuroblasto…](https://mymerci.kr/pages/nclex_q.php?qn_id=542210)
- [A 3-year-old child with neuroblastoma is receiving chemotherapy and has developed severe m…](https://mymerci.kr/pages/nclex_q.php?qn_id=542211)
- [A 3-year-old child with neuroblastoma is receiving chemotherapy and has developed severe m…](https://mymerci.kr/pages/nclex_q.php?qn_id=542212)
- [A 3-year-old child with neuroblastoma is receiving chemotherapy. Which nursing interventio…](https://mymerci.kr/pages/nclex_q.php?qn_id=542213)

---

More free questions: [기출문제](https://mymerci.kr/)

_학습 참고용입니다. 실제 임상은 최신 지침과 소속 기관 프로토콜을 따르세요._