# A 3-year-old child with neuroblastoma is receiving chemotherapy and has developed severe mucositis. The child is refusing to eat and has lost 5% of body weight in the past week. Which nursing intervention should be the priority?

> source: MyMerci (mymerci.kr)  
> url: https://mymerci.kr/pages/nclex_q.php?qn_id=542212  
> language: ko  
> subject: Child Health

## 문제

A 3-year-old child with neuroblastoma is receiving chemotherapy and has developed severe mucositis. The child is refusing to eat and has lost 5% of body weight in the past week. Which nursing intervention should be the priority?

The nurse is caring for a toddler with neuroblastoma who is experiencing treatment-related complications.

## 보기

1. Provide frequent oral care with soft-bristled toothbrush and bland mouth rinses **✔ 정답**
2. Encourage the child to drink citrus juices to stimulate appetite
3. Apply topical anesthetic gel before each meal
4. Increase the frequency of regular meals to compensate for poor intake

**정답: 1**

## 해설

Frequent oral care with gentle techniques is the priority intervention for managing severe mucositis in pediatric oncology patients.

Neuroblastoma is one of the most common extracranial solid tumors in children under 5 years of age. The intensive chemotherapy used to treat this disease causes severe side effects, including mucositis.

Mucositis is a dose-limiting toxicity of chemotherapy that causes inflammation and ulceration of the mucosa throughout the digestive tract, occurring in up to 80% of pediatric cancer patients. Mucositis begins with erythema and progresses to painful ulceration, severely interfering with nutritional intake, increasing infection risk, and reducing quality of life. In this 3-year-old patient, the 5% weight loss indicates the severity of the nutritional impact.

The priority nursing intervention is to maintain oral hygiene while gently approaching the damaged tissue. Frequent oral care using a soft toothbrush and mild oral rinse removes debris, reduces bacterial load, and promotes healing without additional trauma.

Proper oral care for mucositis includes using saline or sodium bicarbonate rinses, avoiding alcohol-based products, and meticulous hygiene to prevent secondary infection. The goal is to manage pain and create an environment conducive to healing while preventing complications that could delay cancer treatment.

## 심화 해설

Understanding the Priority: Managing Severe Mucositis in a Toddler

When a child undergoing chemotherapy develops severe mucositis, the resulting pain and dysphagia create a vicious cycle of reduced oral intake, weight loss, and delayed healing. For this toddler with neuroblastoma who has lost 5% of body weight in one week, the immediate priority is to address the source of the pain and prevent further mucosal breakdown to create a foundation where nutritional intake can eventually resume. The cornerstone of this approach is meticulous, atraumatic oral care.

Why Frequent, Gentle Oral Care is the Priority

The oral cavity of a patient with mucositis is colonized by microbial flora that can exacerbate inflammation and delay re-epithelialization. A consistent oral care protocol directly targets this pathophysiology. The MASCC/ISOO guidelines, evaluated in a pediatric randomized controlled trial, demonstrate that a structured oral care protocol significantly reduces the severity of oral mucositis [1]. This involves mechanical debridement with an ultra-soft or soft-bristled toothbrush to disrupt dental plaque without traumatizing friable mucosa, combined with bland, non-alcoholic mouth rinses (such as normal saline or sodium bicarbonate solutions) to maintain moisture and a neutral oral pH. A quasi-experimental study further supports that basic oral care education provided to children and their parents is effective in preventing and reducing the severity of oral mucositis during chemotherapy cycles [2]. By reducing the microbial load and keeping the mucosa clean and hydrated, this intervention directly decreases the inflammatory stimulus driving the pain, which is the primary barrier to eating.

Analysis of Incorrect Options

- Option 2: Encourage citrus juices. This is contraindicated. The acidic nature of citrus juices will cause intense chemical irritation and burning on denuded mucosal surfaces, significantly worsening the child's pain and tissue breakdown. This directly contradicts the principle of using bland rinses to protect the mucosa.

- Option 3: Apply topical anesthetic gel before meals. While topical anesthetics can provide temporary analgesia to facilitate oral intake, their use is not the first-line priority and carries risks in the pediatric population. Agents like viscous lidocaine can depress the gag reflex, increasing aspiration risk, and systemic absorption through compromised mucosa can lead to toxicity, including seizures. Furthermore, simply numbing the mouth without addressing the underlying microbial and inflammatory environment through oral care provides only a superficial, temporary fix that does not promote healing.

- Option 4: Increase the frequency of regular meals. This intervention ignores the underlying cause of the child's refusal to eat. The child is not anorexic in the traditional sense; they are in severe pain. Increasing the frequency of meal offerings without first mitigating the source of pain will likely increase the child's distress and aversion to eating, potentially worsening the negative caloric balance.

The evidence from the provided meta-analysis and bibliometric review highlights that advanced therapies like photobiomodulation (PBMT) are emerging as effective treatments for chemotherapy-induced oral mucositis [3, 4]. However, these are typically applied as a secondary or adjunctive therapy. The foundational, universally applicable, and immediately actionable nursing intervention that must be established first is a rigorous, atraumatic basic oral care protocol to stabilize the oral environment, control pain at its source, and create the conditions necessary for mucosal healing and eventual nutritional recovery [1, 2].References (research sources)

- [1]Effectiveness of oral mucositis management based on MASCC/ISOO guidelines in pediatric oncology patients: a randomized controlled trial.GuidelineErçelik ZE, Bayram D, Erdoğan B, Altay N. (2026) · DOI: 10.1007/s00520-026-10393-8

- [2]Effect of Basic Oral Care Education Given to Children Receiving Chemotherapy and Their Parents on Oral Mucositis: A Quasi-Experimental Study.Research articleBektaş M, Kobya Bulut H. (2026) · DOI: 10.1080/24694193.2025.2600514

## 임상 시나리오

Pediatric Mucositis Oral Care ProtocolEvidence-based atraumatic care to reduce pain and prevent infection
The priority intervention for chemotherapy-induced mucositis is a structured oral care protocol. Use an ultra-soft or soft-bristled toothbrush for gentle mechanical plaque removal to prevent microbial exacerbation without traumatizing friable tissue.

Rinse the mouth with bland, non-alcoholic solutions such as 0.9% normal saline or sodium bicarbonate solution. This maintains moisture, neutralizes pH, and soothes mucosa. Avoid commercial mouthwashes containing alcohol or phenol.

CautionNever use topical anesthetics like viscous lidocaine before meals in toddlers due to high risk of aspiration from pharyngeal numbness and loss of gag reflex. Acidic juices are contraindicated as they cause severe pain on contact with ulcerated mucosa.

## 핵심 개념

- **Oral Mucositis** — Painful inflammation and ulceration of the oral mucosa, a common side effect of chemotherapy, leading to dysphagia and increased infection risk.
- **MASCC/ISOO Guidelines** — Multinational Association of Supportive Care in Cancer/International Society of Oral Oncology evidence-based recommendations for managing mucositis, emphasizing structured oral care protocols.
- **Bland Mouth Rinse** — Non-alcoholic, non-irritating solutions like normal saline or sodium bicarbonate used to maintain moisture and a neutral oral pH without damaging friable mucosa.
- **Atraumatic Oral Care** — Gentle mechanical debridement using ultra-soft or soft-bristled toothbrushes to remove dental plaque without traumatizing the inflamed mucosal tissue.
- **Cancer Cachexia** — A multifactorial syndrome characterized by ongoing loss of skeletal muscle mass with or without loss of fat mass, often seen in pediatric oncology patients with inadequate nutritional intake.

## 같은 주제 문제

- [A 3-year-old child is admitted to the pediatric oncology unit with a suspected neuroblasto…](https://mymerci.kr/pages/nclex_q.php?qn_id=542207)
- [A 3-year-old child is admitted to the pediatric unit with suspected neuroblastoma. Which a…](https://mymerci.kr/pages/nclex_q.php?qn_id=542208)
- [A 3-year-old child is admitted to the pediatric unit with suspected neuroblastoma. Which a…](https://mymerci.kr/pages/nclex_q.php?qn_id=542209)
- [A 3-year-old child is admitted to the pediatric oncology unit with a suspected neuroblasto…](https://mymerci.kr/pages/nclex_q.php?qn_id=542210)
- [A 3-year-old child with neuroblastoma is receiving chemotherapy and has developed severe m…](https://mymerci.kr/pages/nclex_q.php?qn_id=542211)
- [A 3-year-old child with neuroblastoma is receiving chemotherapy. Which nursing interventio…](https://mymerci.kr/pages/nclex_q.php?qn_id=542213)
- [A 3-year-old child with neuroblastoma is receiving chemotherapy and has developed severe m…](https://mymerci.kr/pages/nclex_q.php?qn_id=542214)

---

More free questions: [기출문제](https://mymerci.kr/)

_학습 참고용입니다. 실제 임상은 최신 지침과 소속 기관 프로토콜을 따르세요._