# A 12-year-old child with aplastic anemia is admitted to the pediatric unit. Which nursing intervention should be the highest priority?

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> url: https://mymerci.kr/pages/nclex_q.php?qn_id=542177  
> language: ko  
> subject: Child Health

## 문제

A 12-year-old child with aplastic anemia is admitted to the pediatric unit. Which nursing intervention should be the highest priority?

The nurse is caring for a pediatric patient with aplastic anemia who has been experiencing fatigue, frequent infections, and easy bruising.

## 보기

1. Implement strict neutropenic precautions and monitor for signs of infection **✔ 정답**
2. Encourage increased physical activity to prevent muscle weakness
3. Provide iron-rich foods to improve hemoglobin levels
4. Administer aspirin for pain management related to bone marrow biopsy

**정답: 1**

## 해설

In aplastic anemia, the bone marrow fails to produce adequate blood cells, resulting in pancytopenia (decreased red blood cells, white blood cells, and platelets). The highest priority is preventing life-threatening infections due to neutropenia.

Aplastic anemia is a serious hematologic condition caused by bone marrow failure, characterized by pancytopenia (decreased red blood cells, white blood cells, and platelets). This disease poses multiple life-threatening risks to pediatric patients.

Pathophysiologically, it results from damage to or destruction of hematopoietic stem cells in the bone marrow, with various possible causes including viral infections, drugs, chemicals, radiation, and autoimmune processes. In many cases, it is idiopathic aplastic anemia with no identifiable cause.

The most important nursing priority is implementing strict neutropenic precautions due to the severely compromised immune system. Neutropenia (low white blood cell count) places the child at extremely high risk for serious and potentially fatal infections, even from normally harmless microorganisms. These precautions include strict hand hygiene, protective isolation, visitor restrictions, no fresh flowers or plants, and monitoring for early signs of infection such as fever, chills, and changes in vital signs.

Clinical manifestations of aplastic anemia include fatigue and pallor (due to anemia), frequent infections and fever (due to neutropenia), and easy bruising, petechiae, and bleeding (due to thrombocytopenia). This combination of symptoms creates a complex clinical picture requiring comprehensive nursing care.

Early detection and prevention of infection are paramount because children with aplastic anemia have a limited ability to fight pathogens. Even a minor infection can rapidly progress to life-threatening sepsis. Since the typical inflammatory response may be blunted due to the lack of white blood cells, nurses must maintain meticulous assessment for subtle signs of infection.

## 심화 해설

Clinical Judgment
This question evaluates Prioritization and Clinical Judgment in a patient with Aplastic Anemia. The core is identifying which of the three major complications of Pancytopenia (infection, bleeding, anemia) is the most acutely life-threatening. Aplastic anemia causes the bone marrow to fail to produce sufficient blood cells, leading to simultaneous Neutropenia, Thrombocytopenia, and Anemia. Among these, infection due to neutropenia can progress most rapidly to Sepsis and death, making it the highest priority for monitoring. Option 3, "elevated temperature with chills," is a critical clue for infection requiring immediate medical intervention.

Memory Tip:
Use **A** **B** **C** to remember the priority. The complications of aplastic anemia are **A**nemia, **B**leeding, and **C**hemotaxis issues (infection). Among these, **C** (infection) is the most **C**ritical.

KR vs US:
While fever in an aplastic anemia patient is also considered an emergency in Korea, the US NGN/NCLEX heavily emphasizes the concept that "Fever in a neutropenic patient is an ONCOLOGIC EMERGENCY." Protocols are strictly established, defining fever in a neutropenic patient as a life-threatening situation where antibiotic administration must begin within 1 hour.

## 임상 시나리오

Clinical Practice Guide: Neutropenic Precautions in Pediatric Aplastic Anemia

For a child with aplastic anemia and severe neutropenia (absolute neutrophil count often < 500 cells/mm³), the immediate priority is preventing infection. This requires a multi-faceted approach.

- **Strict Hand Hygiene:** All staff, visitors, and the patient must perform thorough hand antisepsis before entering the room and before/after any patient contact. This is the single most critical measure.

- **Protective Environment:** Place the patient in a private room with HEPA filtration and positive-pressure airflow to minimize exposure to airborne fungal spores (e.g., Aspergillus). Keep the door closed at all times.

- **Restricted Visitors and Personnel:** Screen all visitors for signs of illness. No live plants or fresh flowers are allowed in the room due to the risk of bacterial and fungal contamination. Staff with any infectious symptoms should not be assigned to the patient.

- **Dietary Modifications:** Implement a low-microbial diet. This excludes raw or undercooked meats, unpasteurized dairy products, and unwashed fresh fruits and vegetables to reduce the ingestion of potential pathogens.

- **Meticulous Skin and Mucous Membrane Care:** Perform daily full-body skin assessments for any breaks in integrity. Use only soft-bristled toothbrushes for oral care and avoid rectal procedures (thermometers, suppositories) to prevent mucosal trauma and entry points for bacteria.

- **Vigilant Monitoring:** Monitor vital signs every 4 hours, with particular attention to even subtle temperature elevations. A single oral temperature of >38.0°C (100.4°F) or sustained >37.8°C (100.0°F) for over an hour is a medical emergency requiring immediate blood cultures, broad-spectrum antibiotics, and notification of the provider.

These interventions are directed at the highest-priority problem: the imminent risk of overwhelming sepsis due to the absence of functional neutrophils. All other care, including psychosocial support and managing fatigue and bleeding risk, is secondary to this protective imperative.

## 핵심 개념

- **Aplastic Anemia** — A rare bone marrow failure disorder resulting in pancytopenia (deficiency of red blood cells, white blood cells, and platelets) due to decreased production of hematopoietic cells.
- **Neutropenic Precautions** — A set of strict infection control measures implemented for patients with severely low neutrophil counts to protect them from acquiring infections from endogenous or environmental sources.
- **Pancytopenia** — A simultaneous deficiency of all three major blood cell lines: erythrocytes (anemia), leukocytes (leukopenia), and thrombocytes (thrombocytopenia).

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