# A 10-year-old child with sickle cell anemia is admitted to the hospital with severe pain crisis. The child rates pain as 9/10 and appears restless and anxious. Vital signs are: temperature 101.2°F (38.4°C), heart rate 120 bpm, respiratory rate 28/min, blood pressure 110/70 mmHg, oxygen saturation 94% on room air. What is the priority nursing intervention? > source: MyMerci (mymerci.kr) > url: https://mymerci.kr/pages/nclex_q.php?qn_id=542135 > language: ko > subject: Adult Health ## 문제 A 10-year-old child with sickle cell anemia is admitted to the hospital with severe pain crisis. The child rates pain as 9/10 and appears restless and anxious. Vital signs are: temperature 101.2°F (38.4°C), heart rate 120 bpm, respiratory rate 28/min, blood pressure 110/70 mmHg, oxygen saturation 94% on room air. What is the priority nursing intervention? The child has been experiencing increasing pain over the past 24 hours, with the pain primarily located in the chest, back, and extremities. The parents report the child has been drinking less fluid than usual due to nausea. Laboratory results show hemoglobin 7.2 g/dL and elevated white blood cell count. ## 보기 1. Administer prescribed antibiotics immediately to prevent infection 2. Encourage increased oral fluid intake to prevent further dehydration 3. Apply cold compresses to painful areas to reduce inflammation 4. Administer prescribed analgesics and provide oxygen therapy **✔ 정답** **정답: 4** ## 해설 Administering prescribed analgesics and providing oxygen therapy are priorities to manage severe pain (9/10) and prevent further sickling from hypoxia (SpO2 94%). Other interventions (antibiotics, fluids, cold compresses) are important but less urgent in this acute crisis. ## 심화 해설 Understanding the Priority: Acute Vaso-Occlusive Crisis Management In a pediatric patient with sickle cell anemia presenting with a severe vaso-occlusive crisis (VOC), the clinical picture you see—severe pain (9/10), tachycardia, tachypnea, fever, and low oxygen saturation—signals a state of significant physiological stress. The priority nursing intervention is guided by the immediate need to interrupt the sickling process and manage the two most critical threats: severe pain and hypoxemia. Option 4, administering prescribed analgesics and providing oxygen therapy, directly addresses these core pathophysiological drivers. Pathophysiology and Clinical Rationale The primary problem in a VOC is microvascular occlusion caused by sickled red blood cells. This leads to tissue ischemia, which is the source of the severe pain. The child's restlessness, anxiety, and vital sign changes (heart rate 120 bpm, respiratory rate 28/min) are physiological responses to this pain and the body's attempt to compensate for decreased oxygen delivery. The hemoglobin of 7.2 g/dL reflects the chronic hemolytic anemia, which reduces the blood's oxygen-carrying capacity. According to the provided guideline, the management of a vaso-occlusive crisis specifically encompasses pain management, hydration, incentive spirometry, and target oxygen saturation levels [1]. Aggressive analgesia is the cornerstone of treatment because uncontrolled pain exacerbates anxiety and increases metabolic oxygen demand, which can worsen sickling. Simultaneously, the child's oxygen saturation is 94% on room air. While this may not seem critically low, in the context of sickle cell disease and a pain crisis, it indicates a ventilation-perfusion mismatch and a risk for developing acute chest syndrome (ACS). The guideline highlights that for ACS, a primary focus is on respiratory support, which includes oxygen therapy to maintain target saturations and prevent further sickling [1]. Administering oxygen reduces the concentration of deoxygenated hemoglobin S, a key factor that triggers the polymerization and sickling of red blood cells. Why Other Options Are Lower Priority - Option 1 (Administer antibiotics): While the presence of fever (101.2°F) and an elevated white blood cell count raises concern for infection, which is a common precipitant of VOC and ACS, the immediate physiological threat is the pain-hypoxia cycle. Antibiotic administration is an important secondary intervention but does not address the acute, severe pain and hypoxemia that are directly causing the patient's current distress and risk of deterioration [1]. - Option 2 (Encourage oral fluids): Hydration is a critical component of VOC management to reduce blood viscosity and slow the sickling process [1]. However, this child is nauseated and has been drinking poorly, making oral intake an unreliable and slow method for urgent rehydration. More importantly, it does not provide immediate relief for a pain score of 9/10 or correct the hypoxemia. Intravenous fluid resuscitation would be a more appropriate and rapid intervention for dehydration, but it still follows the priority of analgesia and oxygenation. - Option 3 (Apply cold compresses): This intervention is contraindicated. Cold causes vasoconstriction and can directly promote or worsen red blood cell sickling in the local area, thereby intensifying the vaso-occlusion and pain. The application of warmth, not cold, is a supportive comfort measure to promote vasodilation. The immediate priority is to break the cycle of pain, anxiety, and hypoxemia that drives the crisis. By administering prescribed analgesics and oxygen, you directly target the underlying pathophysiology, relieve suffering, and prevent the progression to more severe complications like acute chest syndrome, as outlined in the core management strategies for a vaso-occlusive crisis [1].References (research sources) - [1]Guidelines for the management of emergencies and critical illness in pediatric and adult patients with sickle cell disease.GuidelineMekontso Dessap A, Dauger S, Khellaf M, Agbakou M, Agut S, Angoulvant F, Arlet JB, Aubron C, Baudin F, Boissier F, Bounaud N, Catoire P, Cecchini J, Chaiba D, Chauvin A, Chocron R, Douay B, Douillet D, Elenga N, Flechelle O, Gendreau S, Goddet S, Guenezan J, Habibi A, Heilbronner C, Koehl B, Le Borgne P, Le Conte P, Legras A, Levy M, Maitre B, Oberlin M, Oualha M, Peschanski N, Pirenne F, Pondarre C, Rambaud J, Razazi K, Rousseau G, Schirmann A, Thuret I, Valentino R, Voiriot G, Villoing B, Grimaud M, Jean S. (2025) · DOI: 10.1186/s13613-025-01479-3 ## 임상 시나리오 Pediatric Vaso-Occlusive Crisis ManagementPrioritizing Analgesia and Oxygenation The immediate priority in a severe vaso-occlusive crisis (VOC) is to interrupt the sickling process by administering prescribed analgesics and providing oxygen therapy for saturation below 95%. Pain exacerbates hypoxemia and metabolic demand, while hypoxia directly triggers hemoglobin S polymerization. Assess pain using a developmentally appropriate scale and administer opioid analgesics promptly, often via IV for rapid onset. Avoid cold compresses as they cause vasoconstriction and can worsen sickling; apply warm compresses to painful areas instead. CautionDo not delay analgesia for a patient with severe pain. Encourage incentive spirometry to prevent acute chest syndrome, and initiate IV fluid resuscitation rather than oral intake if nausea is present. ## 핵심 개념 - **Vaso-Occlusive Crisis (VOC)** — An acute complication of sickle cell disease where sickled red blood cells obstruct microvasculature, causing severe ischemic pain and potential organ damage. - **Hypoxemia** — Abnormally low concentration of oxygen in the blood, which directly triggers hemoglobin S polymerization and exacerbates sickling. - **Sickling Process** — The reversible process where deoxygenated hemoglobin S molecules polymerize, distorting red blood cells into a rigid, sickle shape that obstructs blood flow. - **Analgesia** — Pain relief; in severe VOC, this typically involves prompt administration of opioid analgesics to reduce pain and metabolic oxygen demand. - **Hemoglobin S (HbS)** — An abnormal form of hemoglobin resulting from a genetic mutation, which causes red blood cells to sickle under conditions of low oxygen, dehydration, or acidosis. ## 같은 주제 문제 - [A nurse is assessing a 35-year-old Hispanic client with sickle cell anemia who presents to…](https://mymerci.kr/pages/nclex_q.php?qn_id=540787) - [A 28-year-old African American client with sickle cell anemia is admitted to the emergency…](https://mymerci.kr/pages/nclex_q.php?qn_id=540788) - [A 35-year-old Hispanic client with sickle cell disease is admitted to the emergency depart…](https://mymerci.kr/pages/nclex_q.php?qn_id=540789) - [A nurse is caring for a 22-year-old client with sickle cell anemia who is experiencing a v…](https://mymerci.kr/pages/nclex_q.php?qn_id=540790) - [A nurse is caring for a 28-year-old African American client with sickle cell anemia who is…](https://mymerci.kr/pages/nclex_q.php?qn_id=540791) - [A 35-year-old African American client with sickle cell anemia is admitted to the emergency…](https://mymerci.kr/pages/nclex_q.php?qn_id=540792) - [A 12-year-old child with sickle cell anemia is admitted to the pediatric unit with complai…](https://mymerci.kr/pages/nclex_q.php?qn_id=542132) - [A 12-year-old child with sickle cell anemia is admitted to the pediatric unit with complai…](https://mymerci.kr/pages/nclex_q.php?qn_id=542133) --- More free questions: [기출문제](https://mymerci.kr/) _학습 참고용입니다. 실제 임상은 최신 지침과 소속 기관 프로토콜을 따르세요._