# A nurse is caring for a client with acute glomerulonephritis. Which nursing assessment finding requires the most immediate intervention?

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## 문제

A nurse is caring for a client with acute glomerulonephritis. Which nursing assessment finding requires the most immediate intervention?

## 보기

1. Blood pressure of 180/110 mmHg with complaints of severe headache **✔ 정답**
2. Urine output of 300 mL in the past 8 hours with mild peripheral edema
3. Serum creatinine level of 2.1 mg/dL (normal: 0.6-1.2 mg/dL)
4. Presence of cola-colored urine with proteinuria on urinalysis

**정답: 1**

## 해설

Severe hypertension with headache indicates hypertensive crisis requiring immediate intervention to prevent stroke or seizure. Other findings are expected in acute glomerulonephritis but less urgent.

## 심화 해설

Priority Assessment: Hypertensive Crisis in Acute Glomerulonephritis

The correct answer is 1. Blood pressure of 180/110 mmHg with complaints of severe headache. This combination of findings signals a hypertensive emergency and impending neurologic complication, which takes precedence over all other listed assessments.

Pathophysiology and Clinical Reasoning

In acute glomerulonephritis, particularly post-streptococcal glomerulonephritis (PSGN), inflammation of the glomeruli leads to a reduction in the glomerular filtration rate (GFR). This causes sodium and water retention, resulting in fluid volume overload and systemic hypertension. The critical danger is not the hypertension itself, but its effect on cerebral autoregulation. When blood pressure rises acutely and severely, the brain's ability to maintain constant perfusion is overwhelmed. This leads to a breakdown of the blood-brain barrier, allowing fluid and proteins to leak into the cerebral interstitium, a condition known as Posterior Reversible Encephalopathy Syndrome (PRES) or hypertensive encephalopathy [1,2].

The client's blood pressure of 180/110 mmHg is severely elevated, and the complaint of a severe headache is a classic early warning sign of this cerebral dysregulation. As documented in the provided case reports, severe headache is a prodromal symptom that can rapidly progress to vomiting, visual disturbances, seizures, and unresponsiveness [1,2]. In one case, a child with PSGN presented with a severe headache three days before developing seizure activity [1]. Another case describes a patient with PSGN who presented with headache, vomiting, and blurred vision before experiencing multiple generalized seizure episodes [2]. Therefore, this assessment finding represents an immediate threat to life and neurological function, requiring the most rapid intervention to lower blood pressure in a controlled manner and prevent irreversible brain injury.

Analysis of Other Options

While all options are abnormal findings consistent with acute glomerulonephritis, they do not represent the same level of immediate threat as a hypertensive crisis with neurological symptoms.

- Option 2: A urine output of 300 mL in 8 hours (which equates to 37.5 mL/hr) indicates oliguria and is a hallmark of the disease process. The mild peripheral edema reflects the expected fluid retention. This finding confirms acute kidney injury (AKI) and requires close monitoring and management, but it does not indicate an impending life-threatening event like a seizure or cerebral hemorrhage .

- Option 3: A serum creatinine of 2.1 mg/dL confirms a significant decrease in kidney function. This laboratory value is a key diagnostic criterion for AKI and guides overall fluid and electrolyte management. However, it is a biochemical marker of severity, not a direct indicator of an imminent neurological catastrophe. The case reports highlight that full renal recovery is possible even after a period of anuria, but a seizure from PRES can cause immediate and permanent harm [1,3].

- Option 4: Cola-colored urine and proteinuria are classic presenting signs of glomerulonephritis caused by red blood cell casts and glomerular membrane damage. These findings are essential for diagnosis but reflect the underlying renal pathology, not an acute, life-threatening complication requiring immediate intervention over a hypertensive crisis.

Nursing Priority and Clinical Application

Using the airway, breathing, circulation (ABCs) and disability (neurological status) prioritization framework, option 1 directly involves a threat to "disability." The severe headache is a symptom of cerebral edema and increased intracranial pressure, which can quickly lead to a loss of airway protective reflexes and respiratory depression during a seizure. The nurse must recognize this combination of severely elevated blood pressure and neurological symptom as a hypertensive emergency and immediately notify the healthcare provider to prepare for rapid, controlled blood pressure reduction, often with intravenous antihypertensives, to prevent the progression to PRES and its devastating sequelae [1,2]. While managing AKI (options 2 and 3) and confirming the diagnosis (option 4) are important, they are secondary to stabilizing a life-threatening hypertensive crisis with neurological manifestations.

References (research sources)

- [1]Posterior Reversible Encephalopathy Syndrome Leading to Diagnosis of Acute Postinfectious Glomerulonephritis in a Pediatric Patient: A Case Report.Case reportHayworth SB, Johnson DL, Schmit EO. (2025) · DOI: 10.1155/crpe/9946572

- [2]Association of Post-streptococcal Glomerulonephritis and Paediatric Posterior Reversible Encephalopathy Syndrome (PRES): A Case Report.Case reportGhanghoriya PK, V RK, M S AA, Jagan J, Rangarh S. (2025) · DOI: 10.7759/cureus.98043

## 임상 시나리오

Hypertensive Crisis in Acute GlomerulonephritisRecognizing and Prioritizing Neurologic Emergencies
In acute glomerulonephritis, fluid retention drives systemic hypertension. A blood pressure of 180/110 mmHg with a severe headache is a classic prodrome of hypertensive encephalopathy, indicating failure of cerebral autoregulation.

This neurologic emergency can rapidly progress to vomiting, visual disturbances, seizures, and unresponsiveness. Immediate intervention focuses on gradual blood pressure reduction to prevent cerebral edema and irreversible brain injury.

CautionDo not delay treatment to manage oliguria or laboratory abnormalities. The priority is the neurologic threat. Lower blood pressure cautiously; rapid drops can cause cerebral ischemia.

## 핵심 개념

- **Hypertensive Encephalopathy** — A neurologic emergency caused by acute, severe hypertension overwhelming cerebral autoregulation, leading to cerebral edema and presenting with severe headache, vomiting, visual changes, and seizures.
- **Acute Glomerulonephritis** — Inflammation of the glomeruli, often post-streptococcal, causing decreased GFR, sodium and water retention, leading to fluid volume overload, hypertension, and hematuria.
- **Cerebral Autoregulation** — The brain's intrinsic ability to maintain constant blood flow despite changes in systemic blood pressure; it fails during extreme acute hypertension, causing capillary leak.

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