# A nurse is caring for a client on peritoneal dialysis who develops cloudy peritoneal effluent with abdominal pain and fever. What is the priority nursing intervention? > source: MyMerci (mymerci.kr) > url: https://mymerci.kr/pages/nclex_q.php?qn_id=541427 > language: ko > subject: Adult Health ## 문제 A nurse is caring for a client on peritoneal dialysis who develops cloudy peritoneal effluent with abdominal pain and fever. What is the priority nursing intervention? ## 보기 1. Obtain a sample of peritoneal effluent for culture and sensitivity testing **✔ 정답** 2. Increase the dwell time of the next dialysis cycle 3. Administer prescribed analgesics for pain relief 4. Encourage increased fluid intake to promote kidney function **정답: 1** ## 해설 Cloudy peritoneal effluent with abdominal pain and fever indicates peritonitis, a serious complication. The priority intervention is to obtain a culture sample before antibiotics to identify the causative organism and guide targeted therapy. ## 심화 해설 Understanding the Clinical Presentation The client’s symptoms of cloudy peritoneal effluent, abdominal pain, and fever constitute the classic triad for peritoneal dialysis-associated peritonitis (PDAP). This is a serious infection of the peritoneal cavity and represents the primary cause of technical failure and infection-related mortality in patients undergoing peritoneal dialysis [3]. The cloudiness of the effluent is caused by an increased concentration of leukocytes, specifically neutrophils, which migrate into the peritoneal cavity in response to infection. The accompanying systemic signs of fever and localized abdominal pain further support an active inflammatory and infectious process within the peritoneum. Prioritizing the Nursing Intervention The priority nursing intervention is to obtain a sample of peritoneal effluent for culture and sensitivity testing. This action is the critical first step in the clinical pathway because it directly enables a definitive diagnosis and guides subsequent, effective treatment. While the clinical presentation strongly suggests peritonitis, confirmation via cell count, Gram stain, and culture is essential. The International Society for Peritoneal Dialysis (ISPD) guidelines, which inform the standard of care, explicitly recommend that effluent cell count and culture should be obtained whenever peritonitis is suspected, and this must be done before initiating empiric antibiotic therapy to maximize the chance of identifying the causative organism. Administering analgesics (Option 3) addresses the patient’s comfort, which is an important but secondary concern. The underlying infectious cause must be identified and treated to resolve the pain definitively. Increasing the dwell time (Option 2) is not a standard intervention for peritonitis and could theoretically worsen the condition by prolonging the exposure of the peritoneal membrane to an infected, hypertonic solution. Encouraging fluid intake (Option 4) is unrelated to the immediate management of peritonitis and is not a priority in this acute infectious scenario. The Critical Role of Effluent Culture The diagnosis of peritonitis hinges on the analysis of the peritoneal effluent. A finding of a white blood cell count greater than 100 cells/µL with at least 50% polymorphonuclear neutrophils is diagnostic. Sending the effluent for culture and sensitivity is the only way to identify the specific pathogen—whether Gram-positive, Gram-negative, or fungal—and determine the most effective antibiotic. This is particularly crucial given the challenges highlighted in the provided evidence. For instance, a significant proportion of peritonitis episodes can be culture-negative, which poses unique management challenges and is associated with specific risk factors and outcomes [3]. Obtaining a proper culture using correct techniques (e.g., inoculating blood culture bottles with a large volume of effluent) is the most effective way to reduce the rate of culture-negative results and avoid prolonged, empiric treatment that may be ineffective or promote resistance. Furthermore, the causative organism profoundly impacts prognosis. Peritonitis caused by non-fermenting Gram-negative bacteria (NF-GNB) has been shown to have distinct clinical characteristics and a different prognosis compared to infections from fermenting Gram-negative bacteria . A case report also illustrates the immense diagnostic and therapeutic challenge of relapsing polymicrobial peritonitis caused by rare NF-GNB pathogens, which can be associated with biofilm formation on the catheter . Without an initial culture to identify the specific pathogen and its sensitivity profile, targeted therapy is impossible, increasing the risk of treatment failure, relapse, catheter loss, and transfer to hemodialysis [1,4]. The inflammatory and nutritional markers such as the neutrophil-to-lymphocyte ratio (NLR) and platelet-to-albumin ratio (PAR), which are significantly altered in peritonitis, underscore the systemic impact of the infection but are supportive findings, not replacements for the definitive microbiological diagnosis obtained from the effluent culture .References (research sources) - [3]Risk factors and outcomes of culture-negative peritonitis in peritoneal dialysis: 10 years' insight from a large center in northern China.Research articleZheng X, Wang H, Zhou Z, Wang Y, Yang W, Xia P, Chen L. (2026) · DOI: 10.1186/s12882-026-04902-4 ## 임상 시나리오 Suspected Peritonitis in Peritoneal DialysisImmediate Steps Before Antibiotics Upon recognizing the classic triad of cloudy effluent, abdominal pain, and fever, the absolute priority is to obtain a peritoneal effluent sample for cell count, Gram stain, and culture. The sample must be collected before initiating any empiric antibiotic therapy to maximize the pathogen identification rate. A dwell time of at least 2 hours is recommended before draining the sample. CautionDo not delay antibiotics unnecessarily after the culture is obtained. If the patient shows signs of sepsis or severe pain, administer empiric antibiotics immediately after specimen collection, targeting both gram-positive and gram-negative organisms per ISPD guidelines. ## 핵심 개념 - **Peritoneal Dialysis-Associated Peritonitis (PDAP)** — A serious infection of the peritoneal cavity indicated by the classic triad of cloudy effluent, abdominal pain, and fever; a leading cause of technique failure in peritoneal dialysis. - **Cloudy Peritoneal Effluent** — Turbid dialysis fluid caused by an elevated leukocyte count (predominantly neutrophils) migrating into the peritoneal cavity in response to infection. - **Effluent Culture and Sensitivity** — A laboratory test performed on a sample of drained dialysis fluid to identify the specific bacterial or fungal pathogen and determine which antibiotics will be effective. - **Empiric Antibiotic Therapy** — Broad-spectrum antibiotics initiated based on the most likely pathogens before culture results are available, which must be started after cultures are obtained. ## 같은 주제 문제 - [A nurse is caring for a client who has been receiving peritoneal dialysis for 6 months. Du…](https://mymerci.kr/pages/nclex_q.php?qn_id=541425) - [A nurse is caring for a client receiving peritoneal dialysis. Which assessment finding wou…](https://mymerci.kr/pages/nclex_q.php?qn_id=541426) - [A nurse is caring for a client receiving peritoneal dialysis who develops cloudy peritonea…](https://mymerci.kr/pages/nclex_q.php?qn_id=541428) - [A nurse is caring for a 65-year-old client on continuous ambulatory peritoneal dialysis (C…](https://mymerci.kr/pages/nclex_q.php?qn_id=541429) - [A nurse is caring for a client receiving peritoneal dialysis who reports severe abdominal …](https://mymerci.kr/pages/nclex_q.php?qn_id=541430) - [A nurse is caring for a 45-year-old client with end-stage renal disease who has been recei…](https://mymerci.kr/pages/nclex_q.php?qn_id=541431) - [A nurse is caring for a client receiving peritoneal dialysis. Which assessment finding wou…](https://mymerci.kr/pages/nclex_q.php?qn_id=541432) --- More free questions: [기출문제](https://mymerci.kr/) _학습 참고용입니다. 실제 임상은 최신 지침과 소속 기관 프로토콜을 따르세요._