# A 35-year-old female client with a history of gallstones presents with severe right upper quadrant pain radiating to the scapula, nausea, vomiting, and elevated serum amylase and lipase levels. Vital signs show: temperature 100.8°F (38.2°C), heart rate 105 bpm, blood pressure 95/65 mmHg, and respirations 22/min. Which nursing action should be the highest priority?

> source: MyMerci (mymerci.kr)  
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> subject: Adult Health

## 문제

A 35-year-old female client with a history of gallstones presents with severe right upper quadrant pain radiating to the scapula, nausea, vomiting, and elevated serum amylase and lipase levels. Vital signs show: temperature 100.8°F (38.2°C), heart rate 105 bpm, blood pressure 95/65 mmHg, and respirations 22/min. Which nursing action should be the highest priority?

## 보기

1. Establish IV access and initiate fluid resuscitation **✔ 정답**
2. Administer prescribed analgesics for pain management
3. Insert a nasogastric tube for gastric decompression
4. Obtain blood samples for additional laboratory tests

**정답: 1**

## 해설

Fluid resuscitation is the highest priority due to hypovolemic shock risk from third-spacing in acute pancreatitis. The client's hypotension, tachycardia, and dry mucous membranes indicate immediate need for IV fluids. Other interventions are secondary to hemodynamic stabilization.

## 심화 해설

Prioritizing Hemodynamic Stabilization in Acute Pancreatitis with Systemic Inflammatory Response

The client's presentation—severe epigastric pain, elevated pancreatic enzymes, and vital sign abnormalities—is consistent with acute pancreatitis (AP). The highest priority nursing action is to Establish IV access and initiate fluid resuscitation. This decision is rooted in the pathophysiology of the disease and the immediate threat to the client's hemodynamic stability.

The combination of a heart rate of 105 bpm and blood pressure of 95/65 mmHg indicates the client is in a state of relative hypovolemia and systemic inflammatory response syndrome (SIRS). In acute pancreatitis, the release of activated pancreatic enzymes triggers a massive inflammatory cascade. This leads to a critical increase in capillary permeability, causing a profound "third-spacing" of intravascular fluid into the retroperitoneum and peritoneal cavity . The resulting intravascular volume depletion can rapidly progress to distributive shock and end-organ failure if not corrected immediately. The referenced case report highlights this exact process, describing how conditions like hypertriglyceridemic acute pancreatitis create a "vicious cycle of metabolic derangements and systemic inflammation," which is a life-threatening emergency requiring prompt, tailored management .

While pain management, gastric decompression, and laboratory tests are all important components of care, they are secondary to restoring circulating volume. Administering analgesics without first ensuring adequate intravascular volume could precipitate a dangerous drop in blood pressure. Similarly, inserting a nasogastric tube and drawing additional labs are interventions that can be safely deferred until fluid resuscitation is underway. The core principle of emergency management is to address the "ABCs" (Airway, Breathing, Circulation). The client’s tachypnea (22/min) and fever (100.8°F / 38.2°C) are further manifestations of the systemic inflammatory response, which aggressive fluid resuscitation aims to mitigate by supporting perfusion and oxygen delivery to tissues . The case report underscores that multidisciplinary collaboration is critical for prompt diagnosis and tailored management, and the nurse's most immediate and independent role in this collaboration is to recognize and treat the circulatory compromise .

## 임상 시나리오

Clinical Guide: Initial Management of Acute Pancreatitis with SIRS

Prioritizing Hemodynamic Resuscitation

Pathophysiology & Clinical Reasoning

The patient's presentation—tachycardia, hypotension, and fever in the setting of elevated pancreatic enzymes—indicates a systemic inflammatory response syndrome (SIRS) driven by acute pancreatitis. The release of activated pancreatic enzymes increases capillary permeability, causing a massive shift of intravascular fluid into the retroperitoneal space (third-spacing). This leads to profound intravascular volume depletion and distributive shock, which is the most immediate threat to life. Fluid resuscitation is the cornerstone of therapy to restore circulating volume and prevent progression to end-organ failure.

Priority Nursing Actions

- **Establish two large-bore IV lines** and initiate aggressive isotonic crystalloid fluid resuscitation (e.g., Lactated Ringer's) as prescribed, often starting with a bolus of 15-20 mL/kg.

- **Monitor hemodynamic response closely:** reassess blood pressure, heart rate, and urine output every 15-30 minutes to evaluate the effectiveness of fluid therapy and detect fluid overload.

- **Assess for signs of end-organ hypoperfusion** such as altered mental status, decreased urine output (less than 0.5 mL/kg/hr), and delayed capillary refill.

- Once hemodynamic stability is achieved, address other priorities including pain management, NPO status, and diagnostic workup.

Clinical Pearls

- Hypotension and tachycardia in pancreatitis should be treated as hypovolemic/distributive shock until proven otherwise.

- Pain management and NG tube placement are important but secondary interventions that should not delay life-saving fluid resuscitation.

- Lactated Ringer's is often preferred over normal saline due to a potentially lower risk of inducing hyperchloremic metabolic acidosis.

## 핵심 개념

- **Third-spacing** — The pathological shift of fluid from the intravascular space into interstitial or body cavities, leading to hypovolemia and edema.
- **Systemic Inflammatory Response Syndrome (SIRS)** — A widespread inflammatory state that can be triggered by conditions like pancreatitis, characterized by abnormal vital signs including tachycardia and hypotension.
- **Hemodynamic Instability** — A state of inadequate blood flow and oxygen delivery to tissues, often indicated by hypotension and tachycardia, requiring urgent intervention.

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