# A nurse is assessing a client with suspected hyperparathyroidism. Which assessment finding would be most indicative of this condition? > source: MyMerci (mymerci.kr) > url: https://mymerci.kr/pages/nclex_q.php?qn_id=540438 > language: ko > subject: Adult Health ## 문제 A nurse is assessing a client with suspected hyperparathyroidism. Which assessment finding would be most indicative of this condition? A 48-year-old female client presents to the clinic with complaints of fatigue, depression, and recent episodes of confusion. She reports having kidney stones twice in the past year and mentions that her bones seem to ache frequently. ## 보기 1. Tetany and muscle spasms 2. Bradycardia and hypothermia 3. Hyperactive deep tendon reflexes 4. Elevated serum calcium levels **✔ 정답** **정답: 4** ## 해설 Hyperparathyroidism causes excessive secretion of parathyroid hormone (PTH), which increases serum calcium levels by promoting calcium release from bones, increasing calcium absorption in the intestines, and enhancing calcium reabsorption in the kidneys. Hyperparathyroidism is a condition in which one or more of the four parathyroid glands excessively secrete parathyroid hormone (PTH). The primary function of PTH is to regulate calcium homeostasis in the body, and excessive secretion leads to hypercalcemia. Pathophysiologically, PTH acts on three main target organs: the bones, kidneys, and intestines. In the bones, PTH stimulates osteoclast activity, promoting bone resorption and releasing calcium into the bloodstream. In the kidneys, it increases calcium reabsorption in the distal tubules and decreases phosphate reabsorption. In the intestines, PTH indirectly increases calcium absorption by stimulating the production of active vitamin D (calcitriol). Elevated serum calcium levels are a characteristic laboratory finding in hyperparathyroidism. Normal serum calcium levels are 8.5-10.5 mg/dL, and exceeding this range indicates hypercalcemia. The clinical symptoms of hypercalcemia can be remembered as "stones, bones, groans, and psychiatric overtones," which refer to kidney stones, bone pain, gastrointestinal symptoms, and neuropsychiatric symptoms, respectively. The fatigue, depression, confusion, recurrent kidney stones, and bone pain that the patient complains of are typical symptoms of hypercalcemia due to hyperparathyroidism. These symptoms occur because elevated calcium affects multiple body systems, including the nervous system (causing confusion and depression), the urinary system (forming kidney stones), and the musculoskeletal system (bone pain due to bone demineralization). From a nursing perspective, early recognition of hyperparathyroidism is crucial. Untreated hypercalcemia can lead to serious complications such as cardiac arrhythmias, severe dehydration, renal failure, and even coma. Nurses should carefully assess for signs and symptoms of hypercalcemia and understand the importance of monitoring serum calcium when it is suspected. ## 심화 해설 Understanding the Clinical Presentation The client's symptoms of fatigue, weakness, bone pain, frequent urination (polyuria), increased thirst (polydipsia), and a history of recurrent kidney stones form a classic clinical picture. These manifestations are direct consequences of the underlying pathophysiology of hyperparathyroidism. In this condition, the parathyroid glands produce excessive parathyroid hormone (PTH). PTH acts on the bones to stimulate osteoclast activity, leading to bone resorption and the release of calcium into the bloodstream, which explains the bone pain and weakness. At the kidneys, PTH promotes calcium reabsorption and phosphate excretion, while also stimulating the conversion of vitamin D to its active form, which further increases intestinal calcium absorption. The resulting state of hypercalcemia impairs the kidneys' ability to concentrate urine, leading to polyuria and compensatory polydipsia. The high levels of calcium filtered through the kidneys also create an environment conducive to the formation of calcium-based kidney stones, aligning with the client's history [3]. Analysis of Laboratory Values The most direct and indicative laboratory finding for hyperparathyroidism is an elevated serum calcium level. The normal range for serum calcium is approximately 8.5-10.5 mg/dL. A value of 11.5 mg/dL represents a state of hypercalcemia, which is the hallmark biochemical abnormality in primary hyperparathyroidism (PHPT) [1,3]. The case report by Patoni et al. specifically documents a patient with hyperparathyroidism presenting with a total calcium level of 11.11 mg/dL, a value very close to the one presented in this question, reinforcing this as a key diagnostic indicator [3]. In contrast, the other options are less specific or not indicative of the primary disorder. - A serum phosphorus level of 4.2 mg/dL is within the normal range. In PHPT, PTH reduces phosphate reabsorption in the kidneys, so the expected finding would be hypophosphatemia (a low serum phosphorus level), not a normal one [1]. - A blood glucose level of 110 mg/dL is only slightly elevated above the normal fasting range and is not a characteristic finding of hyperparathyroidism. While hypercalcemia can theoretically affect insulin secretion, it is not a primary or reliable diagnostic marker for this condition. - A serum magnesium level of 1.8 mg/dL is normal. While severe, complicated cases of hyperparathyroidism can present with hypomagnesemia, as noted in a case report of a patient with a parathyroid crisis and a magnesium level of 0.23 mmol/L, this is a rare finding and not the most indicative or common assessment marker for a typical presentation [1]. Clinical Significance and Diagnostic Reasoning For the NCLEX-RN, recognizing the pattern of hypercalcemia in the context of a patient with bone pain, kidney stones, and gastrointestinal or neuropsychiatric symptoms is critical. The diagnosis of primary hyperparathyroidism is biochemically confirmed by the presence of elevated serum calcium along with an inappropriately normal or elevated PTH level [3,4]. The assessment finding of a serum calcium level of 11.5 mg/dL is the most indicative finding in this scenario because it directly reflects the overproduction of PTH and its effect on bone, kidneys, and the gastrointestinal tract. This single abnormal value should immediately prompt the nurse to suspect hyperparathyroidism and anticipate further diagnostic workup, including a serum PTH level. The other values are either normal or nonspecific, making them less useful as primary indicators of this specific endocrine disorder.References (research sources) - [1]Case Report: Unusual electrolyte changes in primary hyperparathyroidism-a call to suspect underlying Gitelman syndrome.Case reportShantha DWA, Waidyatilleke SR, Senevirathne KP, Dhanushkar R, Jayawickreme KP, Dassanayake BK, Dalugama C, Pathirage M. (2026) · DOI: 10.3389/fendo.2026.1829964 - [3]Recurrent Acute Pancreatitis Secondary to Untreated Hyperparathyroidism: A Case Report and Literature Review.Case reportPatoni C, Popescu SI, Gheorghe C. (2026) · DOI: 10.7759/cureus.111940 ## 임상 시나리오 Clinical Case: Hyperparathyroidism Assessment **Scenario:** A 48-year-old female presents with fatigue, depression, confusion, recurrent kidney stones, and bone pain. **Nursing Action:** The priority assessment finding is elevated serum calcium. This lab value directly reflects the unregulated PTH secretion driving bone resorption and renal calcium reabsorption. **Rationale:** Hypercalcemia is the hallmark of primary hyperparathyroidism. It explains the patient's neuropsychiatric symptoms (fatigue, depression, confusion), renal calculi, and skeletal discomfort. Other options describe manifestations of hypocalcemia, which is the opposite electrolyte disturbance. **Clinical Tip:** Always correlate a high serum calcium with a PTH level. In primary hyperparathyroidism, PTH will be inappropriately normal or elevated despite the hypercalcemia. ## 핵심 개념 - **Hyperparathyroidism** — A condition of excessive parathyroid hormone (PTH) secretion leading to hypercalcemia, bone resorption, and kidney stones. - **Hypercalcemia** — Elevated serum calcium levels, often causing fatigue, depression, confusion, bone pain, and nephrolithiasis. - **Parathyroid Hormone (PTH)** — A hormone that increases serum calcium by stimulating bone resorption, renal calcium reabsorption, and vitamin D activation. - **Tetany** — Involuntary muscle contractions and spasms, classically associated with hypocalcemia, not hypercalcemia. - **Nephrolithiasis** — Kidney stone formation, a common complication of chronic hypercalcemia and hyperparathyroidism. ## 같은 주제 문제 - [A nurse is assessing a 58-year-old client who underwent parathyroidectomy 24 hours ago. 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