# A client taking capivasertib develops intense thirst, frequent urination, nausea, abdominal pain, deep rapid respirations, and positive serum ketones. Which action is the priority?

> source: MyMerci (mymerci.kr)  
> url: https://mymerci.kr/pages/nclex_q.php?qn_id=523000&lang=en  
> language: en  
> subject: Adverse Effects/Contraindications/Interactions  
> category: PPT

## Question

A client taking capivasertib develops intense thirst, frequent urination, nausea, abdominal pain, deep rapid respirations, and positive serum ketones. Which action is the priority?

## Option

1. Give the next capivasertib dose with a sugary beverage.
2. Wait for the next scheduled oncology visit.
3. Treat the findings as expected mild diarrhea.
4. Hold capivasertib immediately and obtain urgent evaluation and treatment for suspected diabetic ketoacidosis. **✔ Correct answer**

**Correct answer: 4**

## Explanation

Capivasertib can cause severe hyperglycemia, diabetic ketoacidosis, and fatal metabolic complications. Suspected ketoacidosis requires immediate withholding and urgent medical management.

## In-depth explanation

Quick answer
Treat hyperglycemic symptoms plus ketones as suspected ketoacidosis.

Why this is correct
Polyuria, polydipsia, abdominal symptoms, deep respirations, and ketones form a metabolic-emergency pattern. Routine delay or additional drug exposure can worsen the decompensation.

Easy analogy or mental picture
Build a medication-safety chain: identify the changing cue, connect it to the labeled toxicity or interaction, interrupt preventable exposure, stabilize the client, and verify a measurable response.

Memory hook
Drug, trend, urgent cue, protective action, and reassessment endpoint.

NCLEX decision rule
Choose the action that prevents the most immediate medication-related harm while preserving indicated treatment and required monitoring.

Why the other choices are wrong
Options that continue a suspect exposure, normalize a labeled danger cue, or delay escalation leave the client at risk.References
1DailyMed: TRUQAP (capivasertib)Severe hyperglycemia and ketoacidosis recognition, immediate interruption, glucose monitoring, diarrhea, and cutaneous toxicity

## Clinical scenario

Oncology medication-safety review
Verify indication, current assessment, laboratory and oxygen trends, interactions, urgent toxicity cues, authorized action, and measurable follow-up.

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