# 一位服用 riociguat 治療肺動脈高壓的個案，在因心臟衰竭住院後，獲得新的 vericiguat 處方。護理師應採取何種行動？

> source: MyMerci (mymerci.kr)  
> url: https://mymerci.kr/pages/nclex_q.php?qn_id=522931&lang=zh-tw  
> language: zh-TW  
> subject: Adverse Effects/Contraindications/Interactions  
> category: PPT

## 題目

一位服用 riociguat 治療肺動脈高壓的個案，在因心臟衰竭住院後，獲得新的 vericiguat 處方。護理師應採取何種行動？

## 選項

1. 給予兩種藥物並僅監測心率。
2. 暫停 vericiguat 並澄清處方，因為合併使用可溶性鳥苷酸環化酶刺激劑是禁忌。 **✔ 正確答案**
3. 未經聯繫處方醫師，永久停止 riociguat。
4. 僅在收縮壓超過 180 mm Hg 時給予 vericiguat。

**正確答案: 2**

## 解析

Vericiguat 與另一種可溶性鳥苷酸環化酶刺激劑（如 riociguat）併用是禁忌，因為這種組合會導致過度低血壓。

## 深入解析

快速解答
不要將 vericiguat 與 riociguat 併用。

為什麼這是正確的
這兩種藥物都刺激可溶性鳥苷酸環化酶。護理師應暫停新藥並解決交互作用的治療方案，而不是自行停用慢性治療。

簡單類比或心像
建立藥物安全鏈：識別新的線索，將其與藥物機制或標示限制連結，停止可預防的暴露，穩定個案，並驗證可測量的反應。

記憶點
藥物、緊急線索、保護性行動和重新評估終點。

NCLEX 決策規則
選擇能預防最直接藥物相關危害的行動，同時保留指示治療和必要的監測。

為什麼其他選項是錯誤的
繼續可疑暴露、將標示的危險線索正常化、替代未經授權的劑量或延遲升級的選項會使個案處於危險之中。References
1DailyMed: VERQUVO (vericiguat)Contraindication with other soluble guanylate cyclase stimulators and hypotension-related interaction safety

## 臨床情境

藥物安全審查
驗證適應症、當前評估、劑量和途徑、器官功能、交互作用、緊急毒性線索、授權行動和可測量的追蹤。

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