# 護理師應根據哪項病史，質疑isavuconazonium的處方？

> source: MyMerci (mymerci.kr)  
> url: https://mymerci.kr/pages/nclex_q.php?qn_id=522887&lang=zh-tw  
> language: zh-TW  
> subject: Adverse Effects/Contraindications/Interactions  
> category: PPT

## 題目

護理師應根據哪項病史，質疑isavuconazonium的處方？

## 選項

1. 季節性過敏性鼻炎
2. 已矯正的近視
3. 遠期闌尾切除術
4. 家族性短QT症候群 **✔ 正確答案**

**正確答案: 4**

## 解析

Isavuconazole會縮短QT間期，因此在家族性短QT症候群中禁用。它還具有重要的強效CYP3A4交互作用限制。

## 深入解析

快速解答
與許多唑類藥物不同，isavuconazole會縮短QT間期。

為何這是正確的
QT效應的方向在臨床上很重要，使家族性短QT症候群成為一個特定的禁忌症。

簡單類比或心像
建立藥物安全鏈：識別新的線索，將其與藥物機制或標示限制連結，停止可預防的暴露，穩定病人，並驗證可測量的反應。

記憶點
藥物、緊急線索、保護措施和再評估終點。

NCLEX決策規則
選擇能預防最直接藥物相關傷害的措施，同時保留指示治療和必要的監測。

為何其他選項是錯誤的
繼續可疑暴露、將標示的危險線索正常化、替代未經授權的劑量或延遲升級的選項會使病人處於危險之中。參考資料
1DailyMed: CRESEMBA (isavuconazonium sulfate)QT間期縮短和家族性短QT禁忌症

## 臨床情境

藥物安全審查
確認適應症、當前評估、劑量和途徑、器官功能、交互作用、緊急毒性線索、授權行動和可測量的後續追蹤。

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