# Place the steps for safe intravenous acyclovir administration to a child in the correct sequence.

> source: MyMerci (mymerci.kr)  
> url: https://mymerci.kr/pages/nclex_q.php?qn_id=522651&lang=en  
> language: en  
> subject: Adverse Effects/Contraindications/Interactions  
> category: PPT

## Question

Place the steps for safe intravenous acyclovir administration to a child in the correct sequence.

Infuse the dose over the ordered period rather than by rapid bolus.

Dilute the dose to the prescribed concentration and prepare a controlled intravenous infusion.

Maintain adequate hydration and track urine output during therapy.

Reassess creatinine and neurologic findings and obtain dose review if renal function worsens.

Verify weight, indication, renal function, hydration status, and the prescribed dose interval.

## Explanation

Safe intravenous acyclovir use begins with patient-specific dose and renal review, followed by correct dilution and controlled infusion, hydration support, and serial renal and neurologic assessment.

## In-depth explanation

Quick answer
Protect the kidneys with verify, dilute, infuse, hydrate, and reassess.

Why this is correct
Rapid bolus administration, dehydration, renal impairment, and other nephrotoxins increase the risk of acyclovir precipitation in renal tubules.

Easy analogy or mental picture
Use a family-centered medication-safety loop: verify age or pregnancy context, identify the exposure and new cue, prevent further harm, stabilize the client, and confirm the response.

Memory hook
Population, indication, dose or route, contraindication, urgent cue, protective action, and reassessment.

NCLEX decision rule
Choose the action that protects the maternal, newborn, or pediatric client from the most immediate medication-related harm while preserving authorized treatment.

Why the other choices are wrong
Options that normalize a danger sign, substitute an unapproved route or dose, or delay reassessment leave the client exposed to preventable harm.References
1DailyMed: intravenous acyclovirCrystal nephropathy, infusion rather than bolus administration, adequate hydration, creatinine-clearance adjustment, and neurologic toxicity

## Clinical scenario

Maternal, newborn, and pediatric medication safety review
Verify the client's age or pregnancy stage, indication, weight or laboratory context, route, interacting therapies, contraindications, caregiver teaching, and measurable follow-up.

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_For study reference only. Always follow current clinical guidelines and your institution’s protocols._