# A hazardous antineoplastic drug container breaks in a medication area. Place the response actions in the safest sequence.

> source: MyMerci (mymerci.kr)  
> url: https://mymerci.kr/pages/nclex_q.php?qn_id=522605&lang=en  
> language: en  
> subject: Adverse Effects/Contraindications/Interactions  
> category: PPT

## Question

A hazardous antineoplastic drug container breaks in a medication area. Place the response actions in the safest sequence.

Clean and decontaminate the area and dispose of waste through the hazardous-drug stream according to policy.

Contain and collect the spill with the designated materials without creating aerosols or spreading contamination.

Obtain the hazardous-drug spill kit and don the task-specific protective equipment in the response plan.

Stop activity, restrict access to the contaminated area, and notify nearby staff.

Remove protective equipment safely, perform hand hygiene, and complete exposure evaluation and incident reporting as indicated.

## Explanation

A controlled response first limits exposure, then applies the planned protective equipment and spill controls, decontaminates the environment, and closes the loop with safe doffing and exposure follow-up.

## In-depth explanation

Quick answer
Sequence isolate, protect, contain, decontaminate, and report.

Why this is correct
Unplanned cleanup can spread hazardous drug contamination to workers and the environment. Facility-specific controls and trained response procedures govern the event.

Easy analogy or mental picture
Use a closed medication-safety loop: identify the immune or cytotoxic exposure, connect the new findings, interrupt further harm, stabilize the client, and verify the response over time.

Memory hook
Exposure, immune effect, organ toxicity, infection risk, immediate action, and serial reassessment.

NCLEX decision rule
Choose the action that reduces the most immediate medication-related risk while preserving diagnostic evaluation and authorized treatment.

Why the other choices are wrong
Options that continue the exposure, treat only one symptom, or delay reassessment leave the toxic or infectious process active.References
1CDC/NIOSH: Managing Hazardous Drug Exposures in Healthcare SettingsRisk assessment, engineering and administrative controls, personal protective equipment, spill response, and exposure follow-up

## Clinical scenario

Oncology, transplant, and biologic safety review
Verify the indication, immune status, infection screen, interacting medicines, current organ findings, authorized action, and measurable follow-up.

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