# 一名服用利那洛肽 (linaclotide) 的病人報告嚴重水樣腹瀉、頭暈和近乎暈厥；血壓為 84/50 mm Hg。哪項措施是優先事項？

> source: MyMerci (mymerci.kr)  
> url: https://mymerci.kr/pages/nclex_q.php?qn_id=522588&lang=zh-tw  
> language: zh-TW  
> subject: Adverse Effects/Contraindications/Interactions  
> category: PPT

## 題目

一名服用利那洛肽 (linaclotide) 的病人報告嚴重水樣腹瀉、頭暈和近乎暈厥；血壓為 84/50 mm Hg。哪項措施是優先事項？

## 選項

1. 額外服用一顆利那洛肽 (linaclotide) 膠囊，以建立更可預測的排便模式。
2. 繼續相同劑量並限制液體攝入，直到腹瀉停止。
3. 暫停利那洛肽 (linaclotide) 並取得緊急評估以及醫囑的液體和電解質補充。 **✔ 正確答案**
4. 除非在下個月便秘再次出現，否則延遲報告此事件。

**正確答案: 3**

## 解析

伴隨低血壓和近乎暈厥的嚴重腹瀉表示臨床上重要的體液流失，需要暫停用藥、補水和緊急評估。

## 深入解析

快速解答
應對 利那洛肽 (linaclotide) 相關的嚴重腹瀉和低灌注。

為何這是正確的
上市後嚴重腹瀉與暈厥、低血壓和電解質異常有關，需要住院或靜脈輸液。

簡單類比或心像
使用閉環式藥物安全流程：識別暴露、連結新發現、中斷進一步傷害、支持生理功能，並隨時間驗證反應。

記憶點
暴露、交互作用、毒性模式、立即行動、連續再評估。

NCLEX 決策規則
選擇能減少最直接藥物相關風險的措施，同時保留監測和升級。

為何其他選項是錯誤的
繼續暴露、僅治療單一症狀或延遲再評估的選項會使毒性過程持續活躍。References
1DailyMed: LINZESS (linaclotide)嚴重腹瀉、劑量暫停、補水、低血壓和電解質異常

## 臨床情境

藥物安全審查
核實適應症、途徑、交互作用藥物、目前的呼吸道和胃腸道發現、授權行動以及可衡量的後續追蹤。

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