# A client taking linaclotide reports severe watery diarrhea, dizziness, and near-syncope; blood pressure is 84/50 mm Hg. Which action is the priority?

> source: MyMerci (mymerci.kr)  
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> language: en  
> subject: Adverse Effects/Contraindications/Interactions  
> category: PPT

## Question

A client taking linaclotide reports severe watery diarrhea, dizziness, and near-syncope; blood pressure is 84/50 mm Hg. Which action is the priority?

## Option

1. Take an extra linaclotide capsule to establish a more predictable bowel pattern.
2. Continue the same dose and restrict fluids until the diarrhea stops.
3. Hold linaclotide and obtain urgent assessment and ordered fluid and electrolyte replacement. **✔ Correct answer**
4. Delay reporting the episode unless constipation returns during the next month.

**Correct answer: 3**

## Explanation

Severe diarrhea with hypotension and near-syncope indicates clinically important volume loss and requires suspension, rehydration, and urgent assessment.

## In-depth explanation

Quick answer
Respond to linaclotide-associated severe diarrhea and hypoperfusion.

Why this is correct
Postmarketing severe diarrhea has been associated with syncope, hypotension, and electrolyte abnormalities requiring hospitalization or intravenous fluids.

Easy analogy or mental picture
Use a closed medication-safety loop: identify the exposure, connect the new findings, interrupt further harm, support physiology, and verify the response over time.

Memory hook
Exposure, interaction, toxicity pattern, immediate action, serial reassessment.

NCLEX decision rule
Choose the action that reduces the most immediate medication-related risk while preserving monitoring and escalation.

Why the other choices are wrong
Options that continue the exposure, treat only one symptom, or delay reassessment leave the toxic process active.References
1DailyMed: LINZESS (linaclotide)Severe diarrhea, dosing suspension, rehydration, hypotension, and electrolyte abnormalities

## Clinical scenario

Medication safety review
Verify the indication, route, interacting medicines, current respiratory and gastrointestinal findings, authorized action, and measurable follow-up.

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