# 一位接受乳果糖治療肝門體循環腦病變的病人。請審查趨勢並選擇最佳的解釋和計畫。

> source: MyMerci (mymerci.kr)  
> url: https://mymerci.kr/pages/nclex_q.php?qn_id=522580&lang=zh-tw  
> language: zh-TW  
> subject: Adverse Effects/Contraindications/Interactions  
> category: PPT

## 題目

一位接受乳果糖治療肝門體循環腦病變的病人。請審查趨勢並選擇最佳的解釋和計畫。

| Time | Data |
| --- | --- |
| Before therapy adjustment | 意識混亂；無排便；鈉 138 mEq/L；鉀 4.0 mEq/L |
| Desired response | 警覺；24 小時內 3 次軟便；維持口服攝取 |
| Current reassessment | 24 小時內 8 次水樣便；血壓 88/52 mm Hg；鈉 150 mEq/L；鉀 3.0 mEq/L |

Q1. 目前的趨勢應如何解釋？

預期的維持反應
乳果糖作用過度，導致體液和電解質流失
預期肝病永久治癒

Q2. 哪項計畫是適當的？

暫停並釐清劑量，評估灌注，並補充醫囑的體液和電解質
增加乳果糖劑量直到所有糞便都呈液狀
忽略這些發現，因為精神狀態已改善

## 解析

預期反應是認知改善，每天排便 2 或 3 次軟便。若進展為頻繁水樣便、低血壓、高血鈉和低血鉀，則表示過度通便以及體液和電解質流失。

## 深入解析

快速答案
平衡腦病變的改善與過度導瀉。

為什麼這是正確的
乳果糖的劑量是根據排便反應來調整的。腹瀉次數增加不一定更好，反而可能導致嚴重的脫水和電解質併發症。

簡單類比或心像
使用閉環式藥物安全流程：識別暴露、連結新發現、中斷進一步傷害、支持生理功能，並隨時間驗證反應。

記憶點
暴露、交互作用、毒性模式、立即行動、連續再評估。

NCLEX 決策規則
選擇能降低最直接藥物相關風險，同時保留監測和升級的行動。

為什麼其他選項是錯誤的
繼續暴露、僅治療單一症狀或延遲再評估的選項會使毒性過程持續活躍。References
1DailyMed: Lactulose Solution劑量調整至每天 2 或 3 次軟便，並避免過度腹瀉和電解質流失

## 臨床情境

藥物安全審查
驗證適應症、途徑、交互作用藥物、目前的呼吸道和胃腸道發現、授權行動以及可測量的後續追蹤。

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